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HCYP3MAG-63K

Millipore

MILLIPLEX® 人细胞因子/趋化因子磁珠板III - 免疫学多重分析

Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in mouse serum, plasma and cell culture samples.

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别名:
Human cytokine multiplex kit, Luminex® human cytokine immunoassay, Millipore human cytokine panel
UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.84

质量水平

种属反应性

human

制造商/商品名称

Milliplex®

assay range

accuracy: 92-106%
standard curve range: 2.0-200,000 pg/mL

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

一般描述

“细胞因子”是用于多种可溶性蛋白质和肽的通用术语,其在正常和病理条件下充当调节剂以调节单个细胞和组织的功能活性。这些蛋白质还介导细胞之间的直接各种相互作用并调节细胞外环境中发生的过程。细胞因子组蛋白包括淋巴因子、干扰素、集落刺激因子和趋化因子。细胞因子和趋化因子研究对于更深入地了解免疫系统及其对大多数抗原的多方面反应以及疾病状态(例如炎症性疾病,过敏反应,肠易激综合征(IBD),脓毒症和癌症)具有重要作用。

MILLIPLEX®人细胞因子/趋化因子面板III使您能够专注于细胞因子的治疗潜力以及细胞因子表达的调节。

.
Luminex® xMAP®平台使用磁珠免疫分析格式,以实现理想的速度和灵敏度,同时定量多种分析物,从而显著提高生产力,同时节省宝贵的样本量。

面板类型:细胞因子/趋化因子

特异性

交叉反应性
抗体与该面板中任何其他分析物之间的交叉反应性都为无法检测或可忽略。

应用

  • 分析物:GCP2、HCC-1、I-TAC、IL-11、IL-29、淋巴细胞肌动蛋白、M-CSF、MIG、MIP-3α、MIP-3β、NAP2
  • 推荐的样品类型:血清,血浆和细胞培养上清液
  • 推荐的样本稀释度:纯血浆或血清。对于血清和血浆样品,NAP-2和HCC-1需要1:100的稀释度
  • 分析运行时间:过夜或2小时初次孵育。为了获得最佳结果,建议过夜孵育
  • 研究类别:炎症 & 免疫学
  • 研究子类别:肥胖,代谢紊乱,炎症 & 自身免疫机制

特点和优势

通过在此面板中选择可用的分析物来设计多重试剂盒。

包装

单个试剂盒即可满足您的所有需求。

储存及稳定性

试剂盒组分建议的存储温度为2-8°C。

其他说明

灵敏度:有关单个细胞因子/趋化因子的灵敏度,请参阅试剂盒方案。
请注意:配置此试剂盒时,必须选择样本类型。 HCC-1/CCL14a和NAP-2/CXCL7不能与血清/血浆的其他分析物复合。

法律信息

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

靶器官

Respiratory Tract

WGK

WGK 3

法规信息

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Marie L Landry et al.
The Journal of infectious diseases, 217(6), 897-905 (2017-12-28)
Despite the high burden of respiratory infection and the importance of early and accurate diagnosis, there is no simple diagnostic test to rule in viral infection as a cause of respiratory symptoms. We performed RNA sequencing on human nasal epithelial
Kristen M Reeder et al.
Mucosal immunology, 11(5), 1352-1362 (2018-06-17)
Asthmatics sensitized to fungi are reported to have more severe asthma, yet the immunopathogenic pathways contributing to this severity have not been identified. In a pilot assessment of human asthmatics, those subjects sensitized to fungi demonstrated elevated levels of the
Matthew S Godwin et al.
American journal of physiology. Lung cellular and molecular physiology, 320(3), L393-L404 (2020-12-17)
Individuals that present with difficult-to-control asthma and sensitivity to one or more fungal species are categorized as a subset of severe asthma patients belonging to a group herein referred to as severe asthma with fungal sensitization (SAFS). We have previously
Alice L den Hertog et al.
PloS one, 10(6), e0129552-e0129552 (2015-06-27)
Many patients treated for tuberculosis (TB) in low and middle income countries are treated based on clinical suspicion without bacteriological confirmation. This is often due to lack of rapid simple accurate diagnostics and low healthcare provider confidence in the predictive
Matthew S Godwin et al.
JCI insight, 4(21) (2019-09-25)
Severe asthma with fungal sensitization (SAFS) defines a subset of human asthmatics with allergy to 1 or more fungal species and difficult-to-control asthma. We have previously reported that human asthmatics sensitized to fungi have worse lung function and a higher

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MILLIPLEX® assays bridge immunology and cell signaling for inflammation studies, including T cell signaling and sepsis signaling.

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