HCVD6MAG-67K

MILLIPLEX^® Human Cardiovascular Disease Magnetic Bead Panel 6 - Cardiovascular Disease (CVD) Multiplex Assay

Name: MILLIPLEX<SUP>®</SUP> Human Cardiovascular Disease Magnetic Bead Panel 6 - Cardiovascular Disease (CVD) Multiplex Assay
Brand: MM

The analytes available for this multiplex kit are: sCD14, DPP4/sCD26, Endostatin, pGRN, LRG1, MCAM, ucMGP

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关于此项目

UNSPSC Code:

12161503

NACRES:

NA.47

eCl@ss:

32161000

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产品名称

MILLIPLEX^® Human Cardiovascular Disease Magnetic Bead Panel 6 - Cardiovascular Disease (CVD) Multiplex Assay, The analytes available for this multiplex kit are: sCD14, DPP4/sCD26, Endostatin, pGRN, LRG1, MCAM, ucMGP

species reactivity

human

manufacturer/tradename

Milliplex^®

assay range

accuracy: 92%
(Endostatin)
accuracy: 95%
(ucMGP)
accuracy: 97%
(DPP4/sCD26)
sensitivity: 0.007 ng/mL
(MinDC+2SD; Endostatin)
sensitivity: 0.014 ng/mL
(MinDC+2SD; pGRN)
sensitivity: 0.015 ng/mL
(MinDC+2SD; LRG1)
sensitivity: 0.016 ng/mL
(MinDC+2SD; MCAM)
sensitivity: 0.016 ng/mL
(MinDC+2SD; sCD14)
sensitivity: 0.041 ng/mL
(MinDC+2SD; DPP4)
sensitivity: 0.052 ng/mL
(MinDC+2SD; ucMGP)
standard curve range: 0.002-10 ng/mL
(Endostatin)
standard curve range: 0.01-40 ng/mL
(sCD14)
standard curve range: 0.024-100 ng/mL
(LRG1)
standard curve range: 0.024-100 ng/mL
(MCAM)
standard curve range: 0.024-100 ng/mL
(pGRN)
standard curve range: 0.049-200 ng/mL
(DPP4/sCD26)
standard curve range: 0.049-200 ng/mL
(ucMGP)
inter-assay cv: <10%
intra-assay cv: <5%
(DPP4/sCD26)
inter-assay cv: <10%
intra-assay cv: <5%
(Endostatin)
inter-assay cv: <10%
intra-assay cv: <5%
(LRG1)
inter-assay cv: <10%
intra-assay cv: <5%
(MCAM)
inter-assay cv: <10%
intra-assay cv: <5%
(pGRN)
inter-assay cv: <20%
intra-assay cv: <10%
(ucMGP)
inter-assay cv: <20%
intra-assay cv: <5%
(sCD14)

technique(s)

multiplexing: suitable

Quality Level

200

detection method

fluorometric (Luminex^® xMAP^® technology)

shipped in

ambient
wet ice

Application

Analytes: Monocyte Differentiation Antigen (CD14/sCD14), Dipeptidyl Peptidase-4 (DPP4/sCD26), Endostatin, Leucine-rich α-2-glycoprotein 1 (LRG1), Cell Surface Glycoprotein (MCAM/ MUC18/sCD146), Progranulin (pGRN), Uncarboxylated Matrix Gla Protein (ucMGP)
Recommended Sample Type:
Human serum, plasma, cell/tissue culture supernatants and lysates
Recommended Sample Dilution: 25 μL per well of 1:500 diluted serum or plasma; cell/tissue culture supernatants or lysates may be used undiluted ore or diluted in appropriate control medium
Assay Run Time: Overnight (16-18 hours)at 2-8°C will yield optimal sensitivity.2- A 2 hour incubation at room temperature (20-25°C) may also be used.
Research Category: Cardiovascular Disease
Research Subcategory: Metabolic Disorders

Biochem/physiol Actions

Cross Reactivty
There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.

Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

Design your multiplex kit by choosing available analytes within this panel.

General description

Cardiovascular disease is one of the major causes of death worldwide. Assessing the risk for cardiovascular disease is an important aspect in clinical decision making and setting a therapeutic strategy. The use of serological biomarkers may significantly facilitate risk factor identification. By exploring new applications of established biomarkers and new approaches to identify novel biomarkers, researchers continue to refine the mechanistic understanding of the biology of CVD diseases.

The MILLIPLEX^® Human Cardiovascular Disease (CVD) Panel 6 is a 7-plex kit may be used to simultaneously quantify any or all the following analytes in human serum, plasma, and tissue culture samples: Soluble Cluster of Differentiation 14 (sCD14), Dipeptidyl Peptidase-4 (DPP4/DPPIV) / Soluble Cluster of Differentiation 26 (sCD26), Endostatin / Collagen Alpha-1 (XVIII) (COL181A), Progranulin (pGRN) / Proepithelin (PEPI) / PC Cell-derived Growth Factor (PCDGF) / Acrogranin / Paragranulin, Leucine-rich Alpha-2-Glycoprotein 1 (LRG1), Melanoma Cell Adhesion Molecule (MCAM) / Soluble Cluster of Differentiation 146 (sCD146) / Cell Surface Glycoprotein MUC18, Uncarboxylated Matrix Gamma-Carboxyglutamate (Gla) Protein (ucMGP). This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex^® xMAP^® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Cardiovascular

Other Notes

Please contact Technical Service for linearity of dilution.

Packaging

Everything you need in a single kit.

Preparation Note

Recommended storage for kit components is 2 - 8°C.

Legal Information

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

pictograms

GHS08,GHS05,GHS07,GHS09

signalword

Danger

hcodes

H302 + H312 + H332,H317,H318,H373,H411

pcodes

P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

10 - Combustible liquids

wgk

WGK 3

法规信息

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MILLIPLEX^® Human Cardiovascular Disease Magnetic Bead Panel 6 - Cardiovascular Disease (CVD) Multiplex Assay