生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
rat, mouse
种属反应性(根据同源性预测)
bovine (based on 100% sequence homology), horse (based on 100% sequence homology), human (based on 100% sequence homology)
技术
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... MPZ(4359)
一般描述
髓鞘蛋白P0也称为外周髓鞘蛋白(MPP)和髓鞘蛋白零(MPZ)。髓鞘蛋白P0仅在外周神经系统中发现,并参与细胞外膜表面的形成,该表面引导包裹过程,最终促使相邻薄片的压实。髓鞘蛋白P0与多种疾病状态有关,包括Charcot-Marie-Tooth病1B(CMT1B),Charcot-Marie-Tooth病2I(CMT2I),Charcot-Marie-Tooth病2J(CMT2J),强直性瞳孔(ADIEP),Charcot-Marie-Tooth病,显性,中间型,D(CMTDID),德热里纳-索塔斯综合征(DSS),先天性髓鞘发育不良神经病(CHN)和Roussy-Levy综合征(ROULS)。
免疫原
对应于人髓鞘蛋白P0胞外域的KLH偶联的线性肽。
应用
免疫组化分析:该抗体的1:2,000稀释液在大鼠脊髓切片中检测到髓鞘蛋白P0。
抗髓鞘蛋白P0抗体是一种高度特异性的兔多克隆抗体,其靶向髓鞘蛋白&已在蛋白质印迹& IHC(石蜡)中进行了测试。
研究子类别
发育神经科学
发育神经科学
研究类别
神经科学
神经科学
质量
通过蛋白质印迹对大鼠脊髓组织裂解物进行了评估。
蛋白质印迹分析:该抗体的1:5,000 的稀释液在 10 µg大鼠脊髓组织裂解物中检测到髓鞘蛋白P0。
蛋白质印迹分析:该抗体的1:5,000 的稀释液在 10 µg大鼠脊髓组织裂解物中检测到髓鞘蛋白P0。
目标描述
观察值〜30 kDa
外形
亲和纯化
在含 0.1 M Tris-甘氨酸(pH 7.4),150 mM NaCl 和 0.05% 叠氮化钠的缓冲液中的纯化的兔多克隆抗体。
储存及稳定性
自收到之日起,在 2-8°C 条件下可稳定保存1年
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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