产品名称
抗-GABA抗体, from rabbit, purified by affinity chromatography
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat
species reactivity (predicted by homology)
all
technique(s)
ELISA: suitable
immunohistochemistry: suitable (paraffin)
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... Gabra1(29705)
Analysis Note
对照
大鼠下丘脑组织
大鼠下丘脑组织
通过免疫组化（石蜡）对大鼠脑组织切片进行了评价。
免疫组化（石蜡）分析：该抗体的1：250 的稀释液在大鼠脑组织切片中检测到GABA。
免疫组化（石蜡）分析：该抗体的1：250 的稀释液在大鼠脑组织切片中检测到GABA。
Application
免疫组化分析：代表性批次的1：500的稀释液在大鼠脑组织中检测到GABA（注意：在血管组织中可能观察到非特异性染色。）。
ELISA分析：来自独立实验室的代表性批次在竞争性ELISA中检测到GABA。
ELISA分析：来自独立实验室的代表性批次在竞争性ELISA中检测到GABA。
抗GABA抗体是一种高度特异性的兔多克隆抗体，其靶向GABA&已在IHC（石蜡）&酶免疫测定（ELISA）中进行了测试。
General description
神经递质可以定义为在被突触后细胞表面的受体结合之前由突触前神经元释放的化学物质。众所周知，神经系统利用神经递质进行细胞信号传导。神经递质可分为两组；低分子量递质分子，例如生物胺，嘌呤或氨基酸，以及生物活性肽，在哺乳动物的中枢神经系统中已鉴定出其中50多个成员。许多低分子量神经递质是在常见的细胞代谢产物的轴突末端产生，并包装到突触囊泡中。含有神经递质的囊泡的转运和传递是一个高度调控的复杂过程。GABA（g-氨基丁酸）是中枢神经系统中的主要抑制性神经递质，与某些神经障碍和精神疾病的发病机理有关。GABA是由谷氨酸在谷氨酸脱羧酶催化的反应中产生的。GABA与GABAA和GABAB受体相互作用，GABAA和GABAB受体广泛分布在整个神经系统和多种细胞类型中。神经递质分子及其前体的免疫定位，神经元分布和囊泡区室化对于理解神经系统中神经递质的调节，调控和功能非常重要。
Other Notes
替代品：AB131
浓度：请参考批次特异性浓缩物的分析证书。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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