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Merck
CN
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主要文件

ABD101

Sigma-Aldrich

Anti-ESRRB Antibody

from rabbit, purified by affinity chromatography

别名:

Steroid hormone receptor ERR2, ERR beta-2, Estrogen receptor-like 2, Estrogen-related receptor beta, ERR-beta, Nuclear receptor subfamily 3 group B member 2

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.75

生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

mouse

种属反应性(根据同源性预测)

human (based on 100% sequence homology)

技术

immunocytochemistry: suitable
western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... ESRRB(2103)

一般描述

The estrogen-related receptor beta (ESRRB) was initially identified in mouse embryonic carcinoma stem cells and was found to be expressed exclusively in trophoblast progenitor cells between days 6.5 and 7.5 post coitum. Recent studies have shown that ESRRB is part of an POU5F1/Oct4-centered protein interaction network in embryonic stem (ES) cells. It is thought to interact with other ES transcription factors such as NANOG within this network, activating POU5F1 transcription and thereby sustaining self-renewal and pluripotency in ES cells.

免疫原

KLH-conjugated linear peptide corresponding to Amino acids 376-388 of Human ESRRB protein.

应用

Immunocytochemical Analysis: 1:50 dilution of this antibody detected ESRRB in a mouse embryonic stem cells.
This Anti-ESRRB Antibody is validated for use in Western Blotting and Immunocytochemistry for the detection of ESRRB.

质量

Evaluated by Western Blot in a mouse brain E16 lysate. Western Blot Analysis: 1μg/ml of this antibody detected ESRRB in a mouse brain E16 lysate. Uncharacterized bands may be observed in some cell lysates with longer exposure times.

目标描述

~56 kDa observed

其他说明

Concentration: Please refer to lot specific datasheet.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Daniela Cornacchia et al.
Cell stem cell, 25(1), 120-136 (2019-06-04)
Current challenges in capturing naive human pluripotent stem cells (hPSCs) suggest that the factors regulating human naive versus primed pluripotency remain incompletely defined. Here we demonstrate that the widely used Essential 8 minimal medium (E8) captures hPSCs at a naive-to-primed intermediate

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