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Merck
CN

AB769

抗IV型胶原抗体

Chemicon®, from goat

别名:

Anti-Anti-BSVD, Anti-Anti-BSVD1, Anti-Anti-COL4A1s, Anti-Anti-PADMAL, Anti-Anti-RATOR

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
dot blot
immunocytochemistry
immunohistochemistry
Species reactivity:
human, bovine, mouse
Citations:
159
Technique(s):
ELISA: suitable
dot blot: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
Uniprot accession no.:
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产品名称

抗IV型胶原抗体, Chemicon®, from goat

Quality Level

Gene Information

human ... COL4A1(1282)

biological source

goat

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, bovine, mouse

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
dot blot: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable

suitability

not suitable for Western blot
not suitable for immunohistochemistry (Paraffin)

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Analysis Note

对照
阳性对照:肾脏、肌肉、肌腱、脾脏组织
阴性对照:神经元/神经胶质

Application

使用经验证可用于DB、ELISA、IC、IH的抗IV型胶原抗体检测IV型胶原。
斑点印迹法和狭线印迹法:1:100-1:500

ELISA:1:1000-1:4000

间接免疫组化(仅冰冻切片):1:10-1:40

免疫细胞化学1:10-1:20

最佳工作稀释度必须由最终用户确定。
研究子类别
ECM 蛋白
研究类别
细胞结构

Biochem/physiol Actions

识别人和牛IV型胶原,如ELISA所示。与I、II、III、V和VI型胶原的交叉反应性低于10%。可能对其他物种的IV型胶原具有反应性。AB769尚未与其他细胞外基质蛋白(例如层粘连蛋白,纤连蛋白)一起检验。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

Immunogen

人和牛胎盘IV型胶原

Other Notes

浓度:请参考批次特异性浓缩物的分析证书。

Physical form

亲和纯化的免疫球蛋白。在纯化之前,将抗血清吸附在固定在琼脂糖4B上的I,II,III,V和VI型胶原上。 硼酸盐缓冲盐水中的液体,pH值8.2,无叠氮化钠。
免疫亲和纯化

Preparation Note

自发运之日起,在 2–8°C 条件下可保存 1 年等分以避免反复冻融。为了最大程度地回收产品,在融化后和取下盖子之前,将原始样品瓶进行离心。

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Sepharose is a trademark of Cytiva

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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Repr. 1B

存储类别

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


分析证书(COA)

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Abigail L Mackey et al.
Skeletal muscle, 7(1), 24-24 (2017-11-09)
While muscle regeneration has been extensively studied in animal and cell culture models, in vivo myogenesis in adult human skeletal muscle has not been investigated in detail. Using forced lengthening contractions induced by electrical stimulation, we induced myofibre injury in
Localization of AQP5 during development of the mouse submandibular salivary gland.
Larsen, HS; Aure, MH; Peters, SB; Larsen, M; Messelt, EB; Kanli Galtung, H
Journal of Molecular Histology null
Christian G M van Dijk et al.
Circulation. Heart failure, 9(4), e002760-e002760 (2016-04-09)
The combination of cardiac and renal disease driven by metabolic risk factors, referred to as cardiorenal metabolic syndrome (CRMS), is increasingly recognized as a critical pathological entity. The contribution of (micro)vascular injury to CRMS is considered to be substantial. However
The histone methyltransferase Setd8 acts in concert with c-Myc and is required to maintain skin.
Driskell, I; Oda, H; Blanco, S; Nascimento, E; Humphreys, P; Frye, M
The Embo Journal null
Daniela Semeniak et al.
Journal of cell science, 129(18), 3473-3484 (2016-08-10)
Collagen receptors GPVI (also known as GP6) and integrin α2β1 are highly expressed on blood platelets and megakaryocytes, their immediate precursors. After vessel injury, subendothelial collagen becomes exposed and induces platelet activation to prevent blood loss. Collagen types I and

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