产品名称
Anti-Calcium Channel γ 4 Antibody, Chemicon®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, human, rat
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CACNG4(27092)
mouse ... Cacng4(54377)
rat ... Cacng4(140725)
Analysis Note
Control
Rat brain lysate.
Rat brain lysate.
Application
Anti-Calcium Channel Antibody, γ 4 detects level of Calcium Channel & has been published & validated for use in WB.
Immunoblotting: 5-10 μg/mL. Reacts with the 36.5 kD protein.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Signaling Neuroscience
Ion Channels & Transporters
Signaling Neuroscience
Biochem/physiol Actions
gamma4 calcium channel (Voltage-Dependant Calcium Channel, gamma4 subunit).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Synthetic peptide from rat gamma4 calcium channel.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.08% sodium azide.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Alterations in AMPA receptor subunits and TARPs in the rat nucleus accumbens related to the formation of Ca??-permeable AMPA receptors during the incubation of cocaine craving.
Ferrario, CR; Loweth, JA; Milovanovic, M; Ford, KA; Gali?anes, GL; Heng, LJ; Tseng, KY; Wolf, ME
Neuropharmacology null
Balakrishnan Selvakumar et al.
Neuropharmacology, 77, 28-38 (2013-09-17)
Behavioral sensitization to cocaine is associated with increased AMPA receptor (AMPAR) surface expression in the nucleus accumbens (NAc). This upregulation is withdrawal-dependent, as it is not detected on withdrawal day (WD) 1, but is observed on WD7-21. Its underlying mechanisms
Carrie R Ferrario et al.
Neuroscience letters, 490(3), 180-184 (2010-12-25)
We characterized the distribution of AMPA receptor (AMPAR) subunits and the transmembrane AMPA receptor regulatory proteins (TARPs) γ-2 and γ-4 in adult rat nucleus accumbens (NAc) using a method that separates plasma membranes into synaptic membrane-enriched and extrasynaptic membrane-enriched fractions.
Samuel W Centanni et al.
Alcoholism, clinical and experimental research, 38(11), 2800-2808 (2014-11-26)
The long-term consequences of adolescent alcohol abuse that persist into adulthood are poorly understood and have not been widely investigated. We have shown that intermittent exposure to alcohol during adolescence decreased the amplitude of GABAA receptor (GABAA R)-mediated tonic currents
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