产品名称
抗黑素细胞刺激素α抗体, serum, Chemicon®
biological source
sheep
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity (predicted by homology)
mammals
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
radioimmunoassay: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... POMC(5443)
Analysis Note
对照
下丘脑
下丘脑
Application
免疫组化：在4%多聚甲醛固定的组织上为1：10,000-1：50,000。
RIA：1：250,000-1：300,000。
最佳工作稀释度必须由最终用户进行确定。
RIA：1：250,000-1：300,000。
最佳工作稀释度必须由最终用户进行确定。
抗促黑素细胞激素抗体，α检测促黑素细胞激素的水平&已发表&已验证可用于IH，RIA。
研究子类别
代谢的CNS控制
激素&受体
代谢的CNS控制
激素&受体
研究类别
神经科学
神经科学
Biochem/physiol Actions
对α-促黑素细胞激素（aMSH），C-末端具有特异性。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
MSH与牛甲状腺球蛋白偶联。
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
未纯化
羊血清。 调理液。不含防腐剂。
Preparation Note
自发运之日起在-20°C可保存1年。等分以避免反复冻融。为了最大程度地回收产品，在融化后和取下盖子之前，将原始样品瓶进行离心。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Gavin A Bewick et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 19(12), 1680-1682 (2005-08-16)
Agouti-related protein (AgRP) and neuropeptide Y (NPY) are colocalized in arcuate nucleus (arcuate) neurons implicated in the regulation of energy balance. Both AgRP and NPY stimulate food intake when administered into the third ventricle and are up-regulated in states of
Amanda H Mortensen et al.
Human molecular genetics, 24(4), 939-953 (2014-10-16)
OTX2 is a homeodomain transcription factor that is necessary for normal head development in mouse and man. Heterozygosity for loss-of-function alleles causes an incompletely penetrant, haploinsufficiency disorder. Affected individuals exhibit a spectrum of features that range from developmental defects in
B E Grayson et al.
Endocrinology, 151(4), 1622-1632 (2010-02-24)
The hypothalamic melanocortin system, which controls appetite and energy expenditure, develops during the third trimester in primates. Thus, maternal nutrition and health may have a profound influence on the development of this system. To study the effects of chronic maternal
Maja Cigrovski Berkovic et al.
Neuroendocrinology, 99(2), 75-84 (2014-04-02)
Although previously considered rare, recent epidemiological studies have revealed that the incidence (3.6/100,000) and prevalence (35/100,000) of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) has increased over the past few decades. Despite the progress in the understanding of GEP-NET molecular biology, there is
Fumihiko Maekawa et al.
Frontiers in synaptic neuroscience, 5, 7-7 (2013-10-10)
We previously reported that the type 2 diabetic Goto-Kakizaki (GK) rats at young adult ages (6-12 weeks) exhibited increased visceral fat mass and hyperleptinemia, due to hyperphagia caused primarily by neuropeptide Y (NPY) overexpression in the hypothalamic arcuate nucleus. Later
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