生物来源
rabbit
质量水平
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
rabbit, rat, mouse, human
制造商/商品名称
Chemicon®
技术
ELISA: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... ALOX5(240)
一般描述
5′-Lipoxygenase is a critical enzyme in the formation of leukotrienes from arachidonic acid. Upon activation, the enzyme translocates to either a nuclear or plasma membrane compartment.
特异性
5′-Lipoxygenase
免疫原
Purified human 5′-Lipoxygenase
应用
Anti-5′-Lipoxygenase Antibody detects level of 5′-Lipoxygenase & has been published & validated for use in ELISA, IP & WB.
Western blot: 1:1,000. Reacts with a 79 kDa band
Immunoprecipitation: 5 μL/mL lysate
ELISA: 1:1000 – 1:100,000
Optimal working dilutions must be determined by the end user.
Immunoprecipitation: 5 μL/mL lysate
ELISA: 1:1000 – 1:100,000
Optimal working dilutions must be determined by the end user.
外形
Format: Purified
Purified immunoglobulin in PBS with 50% Glycerol and 0.02% sodium azide
分析说明
Control
POSITIVE CONTROL: placenta, lung, and leukocytes.
POSITIVE CONTROL: placenta, lung, and leukocytes.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
Fen Yin et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(6), 1153-1161 (2013-04-06)
To evaluate whether exposure to air pollutants induces oxidative modifications of plasma lipoproteins, resulting in alteration of the protective capacities of high-density lipoproteins (HDLs). We exposed apolipoprotein E-deficient mice to diesel exhaust (DE) at ≈ 250 µg/m(3) for 2 weeks
Anna M Adamusiak et al.
International archives of allergy and immunology, 157(4), 354-362 (2011-11-30)
The pathogenesis of rhinosinusitis in aspirin-exacerbated airway disease is closely linked to the disequilibrium in arachidonic acid metabolism. Although considerable amounts of data concerning impaired eicosanoid production are available, the precise mechanism and pathogenesis of the disease are still unknown.
Daryle J DePianto et al.
JCI insight, 6(8) (2021-03-12)
Compromised regenerative capacity of lung epithelial cells can lead to cellular senescence, which may precipitate fibrosis. While increased markers of senescence have been reported in idiopathic pulmonary fibrosis (IPF), the origin and identity of these senescent cells remain unclear, and
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