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Merck
CN

AB3540P

Anti-Monocarboxylate Transporter 1 Antibody

Chemicon®, from rabbit

别名:

MCT1

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, WB
Citations:
16
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SLC16A1(6566)

Immunogen

A 17 amino acid peptide sequence near the C-terminus of rat MCT1 (Gerhart et al. 1997; Knott et al. 1999; Takanaga et al. 1995; Carpenter et al. 1996; Koehler-Stec et al. 1998; Yoon et al. 1999; Halestrap & Price 1999).

Application

Detect Monocarboxylate Transporter 1 using this Anti-Monocarboxylate Transporter 1 Antibody validated for use in ELISA & WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
Western blot: 1-5 μg/mL using ECL. Membrane preps are recommended.



ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Recognizes rat Monocarboxylate Transporter 1 (MCT1). The immunogen shows no significant sequence homology with MCT2-8.

SPECIES REACTIVITIES: The immunogen sequence is 93% conserved in hamster, 80% in mouse and only 40% in human. Reactivity with other species has not been confirmed.

Physical form

Liquid in PBS containing 0.1% BSA .

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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Changzheng Gao et al.
International journal of molecular medicine, 38(6), 1823-1830 (2016-10-26)
The lactate signaling cascade has recently been linked to mitochondrial energy metabolism and cardiomyocyte apoptosis in several cardiovascular diseases. Asiatic acid (AA) exhibits a variety of pharmacological effects, including antioxidant and anti-apoptotic effects. In this study, we investigated the protective effects
Vivian Rodriguez-Cruz et al.
Biopharmaceutics & drug disposition, 42(8), 351-358 (2021-07-01)
Gamma hydroxybutyric acid (GHB) has been approved clinically to treat excessive daytime sleepiness and cataplexy in patients with narcolepsy, alcohol and opioid withdrawal, and as an anesthetic. The use of GHB clinically is limited due to its high abuse potential.
Importance of pH regulation and lactate/H+ transport capacity for work production during supramaximal exercise in humans.
Messonnier, L; Kristensen, M; Juel, C; Denis, C
Journal of Applied Physiology (1985)



全球贸易项目编号

货号GTIN
AB3540P04053252319815