AB3538P
抗单羧酸转运蛋白1抗体
Chemicon®, from rabbit
别名:
MCT1
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA
western blot
western blot
Species reactivity:
human
Citations:
84
Technique(s):
ELISA: suitable
western blot: suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗单羧酸转运蛋白1抗体, Chemicon®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLC16A1(6566)
Application
研究子类别
离子通道 & 转运体
离子通道 & 转运体
研究类别
神经科学
神经科学
蛋白质印迹：使用ECL为1-5μg/mL
ELISA：1：10,000-1：100,000，每孔使用50-100 ng对照肽。
最佳工作稀释度必须由最终用户进行确定。
ELISA：1：10,000-1：100,000，每孔使用50-100 ng对照肽。
最佳工作稀释度必须由最终用户进行确定。
该抗单羧酸转运蛋白1抗体经验证可用于ELISA，WB检测单羧酸转运蛋白1。
Biochem/physiol Actions
可识别人单羧酸转运蛋白1（MCT1）。免疫原与MCT2-8没有明显的序列同源性。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
人MCT1 C末端附近的15个氨基酸肽序列（Gerhart et al. 1997; Knott et al. 1999; Takanaga et al. 1995; Carpenter et al. 1996; Koehler-Stec et al. 1998; Yoon et al. 1999; Halestrap & Price 1999）。
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
亲和纯化的免疫球蛋白。 含0.1%BSA的PBS液体。
Preparation Note
收到货后，在-20°C下以未稀释等分试样可保存长达6个月。应避免反复冻/融循环。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Julieta Afonso et al.
Cell cycle (Georgetown, Tex.), 15(3), 368-380 (2015-12-05)
Monocarboxylate transporters (MCTs) are vital for intracellular pH homeostasis by extruding lactate from highly glycolytic cells. These molecules are key players of the metabolic reprogramming of cancer cells, and evidence indicates a potential contribution in urothelial bladder cancer (UBC) aggressiveness
Expression of monocarboxylate transporters 1, 2, and 4 in human tumours and their association with CD147 and CD44.
Pinheiro, C; Reis, RM; Ricardo, S; Longatto-Filho, A; Schmitt, F; Baltazar, F
Journal of Biomedicine and Biotechnology null
Chun-Kai Huang et al.
Nature communications, 8, 14706-14706 (2017-03-11)
Adipocytes are the most abundant stromal partners in breast tissue. However, the crosstalk between breast cancer cells and adipocytes has been given less attention compared to cancer-associated fibroblasts. Here we find, through systematic screening, that primary mammary gland-derived adipocytes (MGDAs)
S-Nitrosation of monocarboxylate transporter 1: inhibition of pyruvate-fueled respiration and proliferation of breast cancer cells.
Diers, AR; Broniowska, KA; Chang, CF; Hill, RB; Hogg, N
Free radical biology & medicine null
Monocarboxylate transporters, blood lactate removal after supramaximal exercise, and fatigue indexes in humans.
Thomas, C; Perrey, S; Lambert, K; Hugon, G; Mornet, D; Mercier, J
Journal of Applied Physiology (1985)
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