推荐产品
生物来源
rabbit
质量水平
抗体形式
affinity purified immunoglobulin
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
human
制造商/商品名称
Chemicon®
技术
ELISA: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... SLC16A1(6566)
特异性
可识别人单羧酸转运蛋白1(MCT1)。免疫原与MCT2-8没有明显的序列同源性。
免疫原
人MCT1 C末端附近的15个氨基酸肽序列(Gerhart et al. 1997; Knott et al. 1999; Takanaga et al. 1995; Carpenter et al. 1996; Koehler-Stec et al. 1998; Yoon et al. 1999; Halestrap & Price 1999)。
应用
研究子类别
离子通道 & 转运体
离子通道 & 转运体
研究类别
神经科学
神经科学
蛋白质印迹:使用ECL为1-5μg/mL
ELISA:1:10,000-1:100,000,每孔使用50-100 ng对照肽。
最佳工作稀释度必须由最终用户进行确定。
ELISA:1:10,000-1:100,000,每孔使用50-100 ng对照肽。
最佳工作稀释度必须由最终用户进行确定。
该抗单羧酸转运蛋白1抗体经验证可用于ELISA,WB检测单羧酸转运蛋白1。
外形
亲和纯化的免疫球蛋白。 含0.1%BSA的PBS液体。
储存及稳定性
收到货后,在-20°C下以未稀释等分试样可保存长达6个月。应避免反复冻/融循环。
其他说明
浓度:请参考批次特异性浓缩物的分析证书。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Cell cycle (Georgetown, Tex.), 15(3), 368-380 (2015-12-05)
Monocarboxylate transporters (MCTs) are vital for intracellular pH homeostasis by extruding lactate from highly glycolytic cells. These molecules are key players of the metabolic reprogramming of cancer cells, and evidence indicates a potential contribution in urothelial bladder cancer (UBC) aggressiveness
Expression of monocarboxylate transporters 1, 2, and 4 in human tumours and their association with CD147 and CD44.
Journal of Biomedicine and Biotechnology null
S-Nitrosation of monocarboxylate transporter 1: inhibition of pyruvate-fueled respiration and proliferation of breast cancer cells.
Free radical biology & medicine null
Nature communications, 8, 14706-14706 (2017-03-11)
Adipocytes are the most abundant stromal partners in breast tissue. However, the crosstalk between breast cancer cells and adipocytes has been given less attention compared to cancer-associated fibroblasts. Here we find, through systematic screening, that primary mammary gland-derived adipocytes (MGDAs)
The clinicopathological significance of monocarboxylate transporters in testicular germ cell tumors.
Oncotarget, 9(29), 20386-20398 (2018-05-15)
Metabolic reprogramming is one of the hallmarks of cancer. The hyperglycolytic phenotype is often associated with the overexpression of metabolism-associated proteins, such as monocarboxylate transporters (MCTs). MCTs are little explored in germ cell tumors (GCTs), thus, the opportunity to understand
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