推荐产品
生物来源
rabbit
质量水平
抗体形式
affinity purified immunoglobulin
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
human, rat, bovine, mouse, pig
制造商/商品名称
Chemicon®
技术
ELISA: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... SLC9A1(6548)
特异性
Recognizes Na+/H+ Exchanger 1 (NHE1). The immunogen peptide shows no significant homology with other NHE isoforms (NHE2-5).
免疫原
A 22 aa peptide within the cytoplasmic, C-terminal domain of rat NHE1, coupled to KLH.
应用
Detect Na+/H+ Exchanger-1 using this Anti-Na+/H+ Exchanger-1 Antibody validated for use in ELISA & WB.
Western blot: 1-10 μg/mL using Chemiluminescence technique.
ELISA: 1:100,000 using 50-100 ng control peptide per well.
Optimal working dilutions must be determined by end user.
ELISA: 1:100,000 using 50-100 ng control peptide per well.
Optimal working dilutions must be determined by end user.
目标描述
91 kDa
外形
Affinity Purified immunoglobulin. Liquid in PBS and 0.1% BSA .
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 2
Hilmi Burak Kandilci et al.
Frontiers in cardiovascular medicine, 7, 617038-617038 (2021-02-16)
Fully-activated Na+/H+ exchanger-1 (NHE1) generates the cardiomyocyte's largest trans-membrane extrusion of H+ ions for an equimolar influx of Na+ ions. This has the desirable effect of clearing excess intracellular acidity, but comes at a large energetic premium because the exchanged
Bryan J Feger et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 305(10), R1182-R1189 (2013-09-21)
The myocardial Na(+)/H(+) exchanger-1 (NHE1) plays a major role in regulation of intracellular pH, and its upregulation has been implicated in increased ischemia-reperfusion injury and other pathologies. Hydrogen peroxide (H2O2) increases NHE1 activity acutely via ERK1/2 signaling. Chronic strenuous exercise
Chao Huang et al.
Journal of neuroscience research, 93(8), 1192-1202 (2015-02-19)
Inducible nitric oxide synthase (iNOS) critically contributes to inflammation and host defense. The inhibition of heat shock protein 70 (Hsp70) prevents iNOS induction in lipopolysaccharide (LPS)-stimulated macrophages. However, the role and mechanism of endogenous Hsp70 in iNOS induction in microglia
Danny Christiansen et al.
Acta physiologica (Oxford, England), 231(3), e13580-e13580 (2020-11-23)
To assess how blood-flow-restricted (BFR) interval-training affects the capacity of the leg muscles for pH regulation during dynamic exercise in physically trained men. Ten men (age: 25 ± 4y; V˙O2max : 50 ± 5 mL∙kg-1 ∙min-1 ) completed a 6-wk interval-cycling intervention (INT) with one
Zhongyan Lu et al.
Journal of dairy science, 99(1), 733-745 (2015-11-09)
Low sodium content in feed and large amounts of salivary sodium secretion are essential requirements to efficient sodium reabsorption in the dairy cow. It is already known that Na(+)/H(+) exchange (NHE) of the ruminal epithelium plays a key role in
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