生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
monkey, feline, rat, human, mouse, rabbit
制造商/商品名称
Chemicon®
技术
immunohistochemistry: suitable
适用性
not suitable for Western blot
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... SLC6A1(6529)
特异性
GABA转运蛋白-1（GAT-1），C末端。没有检测到与其他发射转运蛋白的C末端的交叉反应性。
免疫原
大鼠GAT-1，C-末端（aa 588-599）
表位：C-端（a.a.588-599）
应用
免疫组化：1:500-1:750，在4%多聚甲醛固定或4%多聚甲醛和0.2%戊二醛固定的组织上。建议用含10%正常山羊血清和0.5%Triton X-100的PBS稀释抗体。AB1570已用于大鼠视网膜、皮层和海马的光学和电子显微镜研究。
注意：不建议将AB1570用于蛋白质印迹。参见AB1570W。
最佳工作稀释度必须由最终用户进行确定。
注意：不建议将AB1570用于蛋白质印迹。参见AB1570W。
最佳工作稀释度必须由最终用户进行确定。
抗GABA转运蛋白-1抗体，C末端（a.a.588-599）是针对GABA转运蛋白-1的抗体，可用于IH。
外形
亲和纯化抗体。 从含1%BSA和0.1%叠氮化钠的0.1 M PBS中冻干。用100 μL无菌蒸馏水复溶。
其他说明
浓度：请参考批次特异性浓缩物的检验报告。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3
WGK
WGK 3
Constantino Sotelo
The Journal of comparative neurology, 506(2), 240-262 (2007-11-21)
The acquisition of the dynamic balance between excitation and inhibition in developing Purkinje cells, necessary for their proper function, is analyzed. Newborn (P0) mouse cerebellum contains glutamatergic (VGLUT2-IR) and gamma-aminobutyric acid (GABA)-ergic (VIAAT-IR) axons. The former prevail and belong to
Elena E Bagley et al.
Neuron, 45(3), 433-445 (2005-02-08)
Adaptations in neurons of the midbrain periaqueductal gray (PAG) induced by chronic morphine treatment mediate expression of many signs of opioid withdrawal. The abnormally elevated action potential rate of opioid-sensitive PAG neurons is a likely cellular mechanism for withdrawal expression.
Xinjun Wang et al.
The Journal of physiology, 592(19), 4257-4276 (2014-08-03)
GABAergic terminals of chandelier cells exclusively innervate the axon initial segment (AIS) of excitatory neurons. Although the anatomy of these synapses has been well-studied in several brain areas, relatively little is known about their physiological properties. Using vesicular γ-aminobutyric acid
Muhamed N H Eeza et al.
Journal of Alzheimer's disease : JAD, 81(2), 797-808 (2021-04-13)
Circadian rhythm disturbance is commonly observed in Alzheimer's disease (AD). In mammals, these rhythms are orchestrated by the superchiasmatic nucleus (SCN). Our previous study in the Tg2576 AD mouse model suggests that inflammatory responses, most likely manifested by low GABA
Pericellular innervation of neurons expressing abnormally hyperphosphorylated tau in the hippocampal formation of Alzheimer's disease patients.
Blazquez-Llorca, L; Garcia-Marin, V; Defelipe, J
Frontiers in Neuroanatomy null
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