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AB1504

Sigma-Aldrich

抗谷氨酸受体1抗体

from rabbit, purified by affinity chromatography

别名:

AMPA 1, AMPA-selective glutamate receptor 1, Glutamate receptor ionotropic, AMPA 1, glutamate receptor, ionotropic, AMPA 1

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1 KIT
CN¥8,017.76

CN¥8,017.76

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1 KIT
CN¥8,017.76

About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

CN¥8,017.76

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获取大包装报价

生物来源

rabbit

质量水平

100

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

rat, horse, mouse, human

种属反应性（根据同源性预测）

platypus (based on 100% sequence homology), equine (based on 100% sequence homology)

技术

immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable

NCBI登记号

NP_000818.2

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Headspace vial, beveled top, rounded bottom volume 20 mL, clear glass vial, O.D. × H × I.D. 23 mm × 75.5 mm × 12.5 mm, for use with PerkinElmer, pkg of 100 ea

SU860049

Headspace vial, beveled top, rounded bottom

material

clear glass vial, round bottom

material

amber glass vial, round bottom

material

clear glass vial, round bottom

material

clear glass vial, round bottom

fitting

thread for 18

fitting

thread for 18

fitting

thread for 18

fitting

thread for 20 mm

volume

20 mL

volume

20 mL

volume

10 mL

volume

20 mL

compatibility

for use with CTC PAL (Varian, Gerstel, Atas, Shimadzu)

compatibility

for use with CTC PAL (Varian, Gerstel, Atas, Shimadzu)

compatibility

for use with CTC HTC PAL, for use with CTC PAL (Varian, Gerstel, Atas, Shimadzu)

compatibility

for use with PerkinElmer

packaging

pkg of 100 ea

packaging

pkg of 100 ea

packaging

pkg of 100 ea

packaging

pkg of 100 ea

一般描述

谷氨酸受体（GluR）可以分为离子型或代谢型，并可再根据其激动剂的偏好型（NMDA、AMPA或海仁藻酸）而进一步分类。存在有四种类型的AMPA选择性GluR亚基（GluR1、GluR2、GluR3和GluR4）。不同亚基的四聚体或五聚体组合有助于AMPA受体的功能多样性。通常，AMPA受体可在大多数兴奋性突触中介导快速突触电流，具有以亚型组成为特征的化学计量。GluR1被认为介导钙内流，并且在与学习有关的突触可塑性中具有至关重要的作用。GluR1的减少是由FMR1基因突变引起的，并有助于脆性X综合征。多巴胺神经元上GluR1受体表达的变化与滥用药物的敏化有关。

特异性

该抗体可识别谷氨酸受体1的胞质结构域。

免疫原

与人谷氨酸受体1细胞质结构域对应的KLH偶联线性肽。
表位：细胞质结构域

应用

免疫组化分析：该抗体的1:300稀释液已显示可检测大鼠脑组织中的谷氨酸受体1（GluR1）。
研究子类别
神经递质& 受体
研究类别
神经科学
该抗谷氨酸受体1抗体经过验证可用在WB，IH（P）IP中检测谷氨酸受体1。

质量

通过蛋白质印迹在小鼠脑裂解物中进行了评估。

蛋白质印迹分析： 该抗体1:1000的稀释液对10 µg 小鼠大脑裂解液中的谷氨酸受体1（GluR1）进行了检测。

目标描述

在~106 kDa处观察到

外形

亲和纯化
纯化的兔多克隆血清，溶于含有0.1 M三甘氨酸（pH 7.4）、150 M NaCl、0.05％叠氮化钠和5mg/ml BSA的缓冲液中。

储存及稳定性

自发运之日起，在 2-8°C 条件下可稳定保存1年

分析说明

对照
小鼠脑裂解液。

其他说明

浓度：请参考批次特异性浓缩物的检验报告。

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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