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Merck
CN
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文件

安全信息

6.18300

Sigma-Aldrich

乙腈

for chromatography (gradient grade 2.5)

别名:

ACN, 乙腈, 氰甲烷, 甲基氰

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About This Item

线性分子式:
CH3CN
CAS号:
分子量:
41.05
Beilstein:
741857
MDL编号:
UNSPSC代码:
12191502

等级

for chromatography (gradient grade 2.5)

质量水平

蒸汽密度

1.41 (vs air)

蒸汽压

72.8 mmHg ( 20 °C)

检测方案

≥99.9% (GC)

形式

liquid

自燃温度

973 °F

expl. lim.

16 %

技术

HPLC: suitable

折射率

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

溶解性

water: soluble (1,000 g/l at 25 °C (77 °F))

密度

0.786 g/mL at 25 °C (lit.)

应用

general analytical

SMILES字符串

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

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一般描述

Acetonitrile is commonly used as a key component in the mobile phase for gradient elution chromatography. It is used in various chromatographic techniques, such as high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS).

应用

Acetonitrile can be used as a mobile phase:
  • Buffer in the liquid chromatographic method for determination of polyamines, amino acids, metanephrines, and catecholamine compounds in human body fluids.
  • Component to facilitate the fast gradient elution separations of polar neutral active pharmaceutical ingredients (APIs).

象形图

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警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

WGK

WGK 2

闪点(°F)

closed cup

闪点(°C)

closed cup

法规信息

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Fast gradient screening of pharmaceuticals with 5 cm long, narrow bore reversed-phase columns packed with sub-3 ?m core?shell and sub-2 ?m totally porous particles
Fekete S, et al.
Talanta, 84(2), 416-423 (2011)
Development and validation of a liquid chromatography-tandem mass spectrometry (LC-MS/MS) procedure for screening of urine specimens for 100 analytes relevant in drug-facilitated crime (DFC)
Remane D, et al.
Analytical and Bioanalytical Chemistry, 406, 4411-4424 (2014)

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