574625
Suramin sodium salt
≥98% (HPLC), crystalline solid, P2Y antagonist, Calbiochem®
别名:
苏拉明，钠盐, P2Y拮抗剂 I，嘌呤能受体P2Y拮抗剂I，PTP抑制剂VI
选择尺寸
关于此项目
desiccated (hygroscopic)
产品名称
苏拉明，钠盐, A reversible and competitive inhibitor of protein tyrosine phosphatases.
SMILES string
[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[S](=O)(=O)([O-])c1cc2c(c(c1)[S](=O)(=O)O)c(ccc2[S](=O)(=O)O)\N=C(/[O-])\c3cc(c(cc3)C)\N=C(/[O-])\c4cc(ccc4)\N=C(\Nc5cc(ccc5)\C(=N\c6c(ccc(c6)\C(=N\c7c8c(c(cc7)[S](=O)(=O)O)cc(cc8[S](=O)(=O)O)[S](=O)(=O)O)\[O-])C)\[O-])
InChI
1S/C51H40N6O23S6.6Na/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80;;;;;;/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80);;;;;;/q;6*+1/p-6
InChI key
VAPNKLKDKUDFHK-UHFFFAOYSA-H
description
Merck USA index - 14, 9006
assay
≥98% (HPLC)
form
crystalline solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
desiccated (hygroscopic)
color
white
solubility
water: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
蛋白质酪氨酸磷酸酶
Disclaimer
General description
Other Notes
Hohenegger, M., et al. 1998.Proc.Natl.Acad.Sci. USA 95, 346.
Waldhoer, M., et al. 1998.Mol.Pharmacol.53, 808.
Zhang, Y.L., et al. 1998.J. Biol. Chem. 273, 12281.
Hohenegger, M., et al. 1996.Mol.Pharmacol.50, 1443.
Emmick, J.J., et al. 1994.J. Pharmacol.Exp.Ther.269, 717.
Denhertog, A., et al. 1992.J. Physiol.454, 591.
Nakajima, M., et al. 1991.J. Biol. Chem.266, 9661.
Wilks, J.W., et al. 1991.Int. J. Radiat.Biol.60, 73.
Huang, R.C., et al. 1990.Mol.Pharmacol.37, 304.
Kopp, R. and Pfeiffer, A. 1990.Cancer Res.50, 6490.
Preparation Note
Legal Information
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
相关内容
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