537059
碘化丙啶
Membrane impermeable DNA intercalator.
别名:
碘化丙啶
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关于此项目
经验公式（希尔记法）:
C27H34I2N4
化学文摘社编号:
分子量:
668.39
UNSPSC Code:
12352200
NACRES:
NA.84
MDL number:
产品名称
碘化丙啶, Membrane impermeable DNA intercalator.
SMILES string
[I-].I.[N+](CCCN1C2=CC(=N)C=CC2=C3C(=C1c4ccccc4)C=C(C=C3)N)(CC)(CC)C
InChI
1S/C27H33N4.2HI/c1-4-31(3,5-2)17-9-16-30-26-19-22(29)13-15-24(26)23-14-12-21(28)18-25(23)27(30)20-10-7-6-8-11-20;;/h6-8,10-15,18-19,29H,4-5,9,16-17,28H2,1-3H3;2*1H/q+1;;/p-1
InChI key
XJMOSONTPMZWPB-UHFFFAOYSA-M
description
RTECS - SF7949600
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
dark red
input
sample type intact cells
fluorescence
λex ~536 nm
λem ~617 nm
shipped in
ambient
storage temp.
2-8°C
Quality Level
相关类别
Biochem/physiol Actions
细胞可渗透性：否
主靶
不渗透膜的DNA嵌入剂
不渗透膜的DNA嵌入剂
产物不与ATP竞争。
可逆：否
Disclaimer
毒性：刺激性（B）
General description
不渗透膜的DNA嵌入剂在488 nm处有红色荧光。可用于流式细胞仪染色凋亡细胞和细胞核。可用于区分凋亡和坏死细胞死亡。可与标记有异硫氰酸荧光素的普通绿色荧光探针一起使用。具有以下光谱特性：消光系数：5,900 M-1cm-1 (493 nm)；55,700 M-1cm-1 (287 nm)；13,800 M-1cm-1 (252.5 nm)；最大发射波长：536 nm；最大发射波长：617 nm。
消光系数（493 nm）：5900 M -1cm-1；(287 nm)：55,700 M -1cm-1；
Other Notes
Belloc, F., et al. 1994.Cytometry 17, 59.
Crompton, T., et al. 1992.Biochem.Biophys.Res. Commun.183, 532.
Darzynkiewicz, Z., et al. 1992.Cytometry13, 795.
de Caestecker, M.P., et al. 1992.J. Immunol. Methods154, 11.
Pollice, A.A., et al. 1992.Cytometry13, 432.
Crompton, T., et al. 1992.Biochem.Biophys.Res. Commun.183, 532.
Darzynkiewicz, Z., et al. 1992.Cytometry13, 795.
de Caestecker, M.P., et al. 1992.J. Immunol. Methods154, 11.
Pollice, A.A., et al. 1992.Cytometry13, 432.
Preparation Note
复溶后，等分并冷冻保存（-20°C）。贮备溶液在-20°C下可稳定保存至多6个月。
首先溶解在非常少量的DMSO中，然后向水溶液中添加材料，可以改善溶解度。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Muta. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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