495417-M
N-Oleoyl Ethanolamine
A potent inhibitor of the ceramidase found in human kidney and cerebellum.
别名:
N-Oleoyl Ethanolamine, N-2-Hydroxyethyl-9(Z)-octadecenamide, AC Inhibitor I, Acid Ceramidase Inhibitor I, OEA
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关于此项目
经验公式（希尔记法）:
C20H39NO2
化学文摘社编号:
分子量:
325.53
UNSPSC Code:
12352211
MDL number:
NACRES:
NA.77
SMILES string
N(CCO)C(=O)CCCCCCC\C=C/CCCCCCCC
InChI
1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-
InChI key
BOWVQLFMWHZBEF-KTKRTIGZSA-N
assay
≥98% (TLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
chloroform: 5 mg/mL, ethanol: 5 mg/mL, methanol: 5 mg/mL
storage temp.
−20°C
Quality Level
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General description
A potent inhibitor of the ceramidase found in human kidney and cerebellum. Blocks the conversion of ceramide to sphingosine. A specific inhibitor of acid ceramidase (IC50 ~ 500 µM).
Biochem/physiol Actions
Primary Target
Acid ceramidase
Acid ceramidase
Target IC50: ~ 500 µM against acid ceramidase
Other Notes
Pahan, K., et al. 1998. J. Biol. Chem. 273, 2591.
Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
Sugita, M., et al. 1975. Biochim. Biophys. Acta398, 125.
Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206.
Sugita, M., et al. 1975. Biochim. Biophys. Acta398, 125.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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