48-684MAG
MILLIPLEX® Ras-Raf Oncoprotein Signaling Panel
Premixed Human Ras-Raf Oncoprotein 6-Plex Cell Signaling Panel
别名:
Cell Signaling Assay, MAPK cascade assay, MEK1/ERK1/2 panel, Raf kinase assay, Ras pathway ELISA, Ras-Raf assay, Ras-Raf phosphoprotein panel, oncogene signaling multiplex, phospho-Raf
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关于此项目
NACRES:
NA.47
UNSPSC Code:
12161503
产品名称
MILLIPLEX® Ras-Raf Oncoprotein Signaling Panel,
description
Premixed Human Ras-Raf Oncoprotein 6-Plex Cell Signaling Panel
product line
Milliplex®
species reactivity
human
packaging
pkg of 1 ea
technique(s)
multiplexing: suitable
input
cell lysate
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
General description
This panel targets phosphorylated proteins in the Ras-Raf signaling cascade, a key pathway in cell proliferation and oncogenesis. It includes c-Raf (pS338), MEK1 (pS217/pS221), ERK1/2 (pT185/pY187), and downstream effectors such as p90RSK (pT359/pS363). Dysregulation of this pathway is commonly associated with various cancers, making this panel ideal for oncology and signal transduction research.
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 6 analytes in cell lysate samples.
Analytes Included: c-Raf (Phospho-Ser338), MEK1 (Phospho-Ser217/221), ERK1/2 (Phospho-Thr185/Tyr187), p90RSK (Phospho-Thr359/Ser363)
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).
Analytes Included: c-Raf (Phospho-Ser338), MEK1 (Phospho-Ser217/221), ERK1/2 (Phospho-Thr185/Tyr187), p90RSK (Phospho-Thr359/Ser363)
Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate™ Control Assays).
Features and Benefits
- Simultaneously detect 6 phosphorylated proteins in the Ras-Raf-MEK-ERK signaling cascade
- Includes c-Raf, MEK1, ERK1/2, and p90RSK
- Magnetic bead-based format ensures reproducibility and efficient processing
- Compatible with cell lysates from cancer, proliferation, and signal transduction studies
- Ideal for oncology, targeted therapy research, and MAPK pathway analysis
- Fast, convenient alternative to Western Blotting and immunoprecipitation procedures"
Legal Information
Luminex is a registered trademark of Luminex Corporation
MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
For research use only. Not for use indiagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which containsfluorescently labeled microsphere beads authorized by Luminex Corporation) orusing this Assay Product in any manner, you are consenting and agreeing to bebound by the End User Terms and Conditions and the End User License Agreementavailable at http://support.diasorin.com/end-user-terms-and-conditions/. If youdo not agree to all of the terms and conditions, you must promptly return thisAssay Product for a full refund prior to using it in any manner.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which containsfluorescently labeled microsphere beads authorized by Luminex Corporation) orusing this Assay Product in any manner, you are consenting and agreeing to bebound by the End User Terms and Conditions and the End User License Agreementavailable at http://support.diasorin.com/end-user-terms-and-conditions/. If youdo not agree to all of the terms and conditions, you must promptly return thisAssay Product for a full refund prior to using it in any manner.
signalword
Danger
存储类别
10 - Combustible liquids
wgk
WGK 3
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2