324713
Glu-C Protease
Selectively cleaves at glutamic acid residues, suitable for mass spectromety, from Staphylococcus aureus
别名:
内蛋白酶Glu-C，切除级，金黄色葡萄球菌, V8蛋白酶
产品名称
内蛋白酶Glu-C，切除级，金黄色葡萄球菌,
biological source
Staphylococcus aureus
grade
Proteomics Grade
form
lyophilized
specific activity
≥10 units/mg protein
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
ambient
storage temp.
2-8°C
Quality Level
Disclaimer
毒性：有害（C）
General description
来源于金黄色葡萄球菌的天然内蛋白酶Glu-C。一种特异性水解谷氨酸和天冬氨酸残基羧基侧肽键的丝氨酸蛋白酶。受DFP和α2-巨球蛋白抑制。建议的工作浓度：1:20至1:100（按重量计，蛋白酶：蛋白质）用于序列分析。
Other Notes
Houmard, J., and Drapeau, G.R.1972.Proc.Natl.Acad.Sci. USA69, 3506.
一个单位定义为在25°C，pH 7.8下，每分钟水解1.0 µmol Z-Phe-Leu-Glu-pNA的酶量。
Preparation Note
复溶后，等分并冷冻长期保存（-20°C），或冷藏（4°C）短期保存。储备溶液在4°C下可稳定保存2天，在-20°C下可稳定保存1个月。
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
S Zhang et al.
The Journal of biological chemistry, 271(52), 33575-33579 (1996-12-27)
While multiple G protein beta and gamma subunit isoforms have been identified, the implications of this potential diversity of betagamma heterodimers for signaling through betagamma-regulated effector pathways remains unclear. Furthermore the molecular mechanism(s) by which the betagamma complex modulates diverse
Victoria L Stefanelli et al.
Matrix biology : journal of the International Society for Matrix Biology, 82, 86-104 (2019-04-21)
The extracellular matrix (ECM) microenvironment is increasingly implicated in the instruction of pathologically relevant cell behaviors, from aberrant transdifferentation to invasion and beyond. Indeed, pathologic ECMs possess a panoply of alterations that provide deleterious instructions to resident cells. Here we
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