product name
D-(–)-2-氨基-5-膦酰戊酸, Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist.
质量水平
检测方案
≥97% (HPLC)
形式
solid
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
desiccated (hygroscopic)
protect from light
颜色
white
溶解性
dilute aqueous base: 1 mg/mL
water: 1 mg/mL
运输
ambient
储存温度
2-8°C
InChI
1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)/p-2/t4-/m1/s1
InChI key
VOROEQBFPPIACJ-SCSAIBSYSA-L
一般描述
一种DL-2-氨基-5-膦基戊酸（AP5）的活性对映体，是一种常用的竞争性NMDA受体拮抗剂。
一种DL-2-氨基-5-膦基戊酸（AP5）的活性对映体，通常用作竞争性NMDA受体拮抗剂。还抑制辣椒素诱导的脊髓物质P的释放。
生化/生理作用
主要靶标
NMDA受体拮抗剂
NMDA受体拮抗剂
产物不与ATP竞争。
可逆：否
细胞渗透性：否
警告
毒性：刺激性（B）
重悬
复溶后，等分并冷冻保存（-20°C）。储备液在-20°C条件下可稳定保存6个月。
其他说明
Malcangio, M., et al. 1998.Br. J. Pharmacol.125, 1625.
Schulte, M.K., et al. 1994.Brain Res. 649, 203.
Davis, S., et al. 1992.J. Neurosci. 12, 21.
Schulte, M.K., et al. 1994.Brain Res. 649, 203.
Davis, S., et al. 1992.J. Neurosci. 12, 21.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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