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Merck
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16-310

Sigma-Aldrich

Anti-Nitrotyrosine Magnetic Bead Conjugate Antibody

from rabbit

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性(根据同源性预测)

all

技术

immunoprecipitation (IP): suitable

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... NOS1(4842)

一般描述

Nitrotyrosine has been identified as an indicator of cell damage and inflammation, as well as of the production of NO. It is believed that measuring the concentration of nitrotyrosine will serve as a marker for damage caused by NO in the cell. Previous studies have shown that nitrotyrosine has been found in inflammatory conditions such as atherosclerotic plaques and rheumatoid arthritis, among others.

免疫原

Nitrated KLH

应用

Anti-Nitrotyrosine Magnetic Bead Conjugate Antibody is an antibody against Nitrotyrosine for use in IP.
Research Category
Signaling
Research Sub Category
General Post-translation Modification

质量

Evaluated by immunoprecipitation on A431 whole cell lysate stimulated with 10 mM Peroxynitrite (5 minutes).

目标描述

Varies

外形

Immunoaffinity Chromatography
20% slurry; 1x PBS, 0.05% sodium aside.
Sufficient for 10 IPs.
Format: Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of shipment. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

分析说明

Control
A431 whole cell lysate stimulated with 10 mM Peroxynitrite (5 minutes).

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Andrew Stiff et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 24(8), 1891-1904 (2018-01-25)
Purpose: mAbs are used to treat solid and hematologic malignancies and work in part through Fc receptors (FcRs) on natural killer cells (NK). However, FcR-mediated functions of NK cells from patients with cancer are significantly impaired. Identifying the mechanisms of

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