14-687-M
p38α/SAPK2a (T106M) Protein, active, 10 µg
Active, N-terminal GST-tagged, recombinant, human, full-length p38α/SAPK2a containing the mutation T106M. Activated using DD-MKK6 & repurified using glutathione-agarose. For use in Kinase Assays.
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About This Item
UNSPSC代码:
12352202
eCl@ss:
32160405
NACRES:
NA.32
生物来源
human
质量水平
100
300
重组
expressed in E. coli
分子量
Mw 67.7 kDa
制造商/商品名称
Upstate®
技术
activity assay: suitable (kinase)
UniProt登记号
基因信息
human ... MAPK14(1432)
一般描述
N-terminal GST-tagged, recombinant, human, full-length p38α/SAPK2a containing the mutation T106M. Activated using DD-MKK6 (14-537) and repurified using glutathione- agarose.
Contains the gatekeeper mutation T160M in the ATP-binding domain. This mutation increases resistance to SB203580 as compared to the wild type sequence.
Contains the gatekeeper mutation T160M in the ATP-binding domain. This mutation increases resistance to SB203580 as compared to the wild type sequence.
Product Source: Human, full-length p38α/SAPK2a containing the mutation T106M. Expressed in E. coli.
质量
routinely evaluated by phosphorylation of MBP (13-104).
其他说明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
10 - Combustible liquids
WGK
WGK 2
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