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生物来源
human
质量水平
重组
expressed in Sf21 cells
分子量
Mw 83 kDa
制造商/商品名称
Upstate®
技术
activity assay: suitable (kinase)
NCBI登记号
UniProt登记号
基因信息
human ... PRKCQ(5588)
一般描述
Product Source: expressed in Sf21 cells
Recombinant full-length human PKC theta with a C-terminal 6His-tag
PKC Lipid activator (Catalog # 20-133) is required for use.
PKC Lipid activator (Catalog # 20-133) is required for use.
生化/生理作用
Protein Target: PKCθ
Target Sub-Family: AGC
质量
routinely evaluated by phosphorylation of Histone H1 substrate in vitro
外形
immobilized nickel affinity chromatography
储存及稳定性
6 months at -70 °C
其他说明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
警示用语：
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
G Baier et al.
The Journal of biological chemistry, 268(7), 4997-5004 (1993-03-05)
Members of the protein kinase C (PKC) family of serine/threonine kinases play a key role in regulating the differentiation and growth of diverse cell types and, to date, the cloning of seven mammalian PKC genes encoding eight distinct isoforms has
B Bauer et al.
The Journal of biological chemistry, 276(34), 31627-31634 (2001-06-19)
Protein kinase C theta (PKC theta) is known to induce NF-kappa B, an essential transcriptional element in T cell receptor/CD28-mediated interleukin-2 production but also T cell survival. Here we provide evidence that PKC theta is physically and functionally coupled to
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