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生物来源
mouse
质量水平
100
300
分子量
Mw 67.7 kDa
制造商/商品名称
Upstate®
技术
activity assay: suitable (kinase)
NCBI登记号
UniProt登记号
基因信息
mouse ... MAP2K4(26398)
一般描述
N-terminal GST tagged, murine MKK4 residues 34-end
Product Source: expressed in E. coli
生化/生理作用
Protein Target: MKK4
Target Sub-Family: STE
包装
Also available in 250 µg size --call for pricing and availability and reference catalog number 14-377M when ordering the 250 µg size.
质量
routinely evaluated by phosphorylation of ATF2 substrate
外形
Purified using glutathione agarose. Activated by incubation with MEKK and then re-purified using Ni2+/NTA agarose
储存及稳定性
6 months at -70C
其他说明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
警示用语：
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Y Fleming et al.
The Biochemical journal, 352 Pt 1, 145-154 (2000-11-04)
Stress-activated protein kinase 1 (SAPK1), also called c-Jun N-terminal kinase (JNK), becomes activated in vivo in response to pro-inflammatory cytokines or cellular stresses. Its full activation requires the phosphorylation of a threonine and a tyrosine residue in a Thr-Pro-Tyr motif
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