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Merck
CN
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14-377-M

Sigma-Aldrich

MKK4/SKK1 Protein, active, 10 µg

Active, N-terminal GST tagged, murine MKK4 residues 34-end, for use in Kinase Assays.

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UNSPSC代码:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物来源

mouse

质量水平

100
300

分子量

Mw 67.7 kDa

制造商/商品名称

Upstate®

技术

activity assay: suitable (kinase)

NCBI登记号

UniProt登记号

基因信息

mouse ... MAP2K4(26398)

一般描述

N-terminal GST tagged, murine MKK4 residues 34-end
Product Source: expressed in E. coli

生化/生理作用

Protein Target: MKK4
Target Sub-Family: STE

包装

Also available in 250 µg size --call for pricing and availability and reference catalog number 14-377M when ordering the 250 µg size.

质量

routinely evaluated by phosphorylation of ATF2 substrate

外形

Purified using glutathione agarose. Activated by incubation with MEKK and then re-purified using Ni2+/NTA agarose

储存及稳定性

6 months at -70C

其他说明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Skin Sens. 1

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Y Fleming et al.
The Biochemical journal, 352 Pt 1, 145-154 (2000-11-04)
Stress-activated protein kinase 1 (SAPK1), also called c-Jun N-terminal kinase (JNK), becomes activated in vivo in response to pro-inflammatory cytokines or cellular stresses. Its full activation requires the phosphorylation of a threonine and a tyrosine residue in a Thr-Pro-Tyr motif

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