生物来源
human
质量水平
重组
expressed in Sf21 cells
分子量
Mw 49.2 kDa
制造商/商品名称
Upstate®
技术
activity assay: suitable (kinase)
UniProt登记号
运输
dry ice
基因信息
human ... MAPK9(5601)
一般描述
N-terminal His6-tagged, recombinant, full-length, human JNK2α2/SAPK1a unactive
Product Source: Expressed in Sf21 insect cells
生化/生理作用
Protein Target: JNK2α2/SAPK1a
Target Sub-Family: CMGC
质量
Routinely evaluated by phosphorylation of JNK2α2/SAPK1a
外形
Ni2+/NTA-agarose
储存及稳定性
1 year at -20°C
其他说明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
警示用语：
Warning
危险声明
危险分类
Skin Sens. 1
储存分类代码
10 - Combustible liquids
WGK
WGK 2
S Gupta et al.
The EMBO journal, 15(11), 2760-2770 (1996-06-03)
The JNK protein kinase is a member of the MAP kinase group that is activated in response to dual phosphorylation on threonine and tyrosine. Ten JNK isoforms were identified in human brain by molecular cloning. These protein kinases correspond to
S Gupta et al.
Science (New York, N.Y.), 267(5196), 389-393 (1995-01-20)
Treatment of cells with pro-inflammatory cytokines or ultraviolet radiation causes activation of the c-Jun NH2-terminal protein kinase (JNK). Activating transcription factor-2 (ATF2) was found to be a target of the JNK signal transduction pathway. ATF2 was phosphorylated by JNK on
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