生物来源
human
质量水平
重组
expressed in E. coli
分子量
Mw 80.6 kDa
制造商/商品名称
Upstate®
技术
activity assay: suitable (kinase)
NCBI登记号
UniProt登记号
运输
dry ice
基因信息
human ... MAP2K6(5608)
一般描述
Product Source: expressed in E. coli
Recombinant human MKK6, amino acids 4-end, fused at the N-terminus to a Mal-E tag
生化/生理作用
Protein Target: MKK6
Target Sub-Family: STE
质量
routinely evaluated by phosphorylation of MBP
外形
affinity chromatography on amylose resin beads
储存及稳定性
6 months at -70C
其他说明
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
警示用语：
Warning
危险声明
危险分类
Skin Sens. 1
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
A Dominic Fortes
Acta crystallographica. Section E, Crystallographic communications, 71(Pt 7), 799-806 (2015-08-19)
Time-of-flight neutron powder diffraction data have been measured from ∼90 mol% deuterated isotopologues of Na2MoO4·2H2O and Na2WO4·2H2O at 295 K to a resolution of sin (θ)/λ = 0.77 Å(-1). The use of neutrons has allowed refinement of structural parameters with a precision that varies
Sandeep B Adavi et al.
Bio-protocol, 9(20), e3402-e3402 (2019-10-20)
Nitric oxide (NO), is a redox-active, endogenous signalling molecule involved in the regulation of numerous processes. It plays a crucial role in adaptation and tolerance to various abiotic and biotic stresses. In higher plants, NO is produced either by enzymatic
Romina Bertinat et al.
Journal of cellular physiology, 232(2), 355-362 (2016-10-31)
Diabetic kidney disease (DKD) is the major cause of end stage renal disease. Sodium tungstate (NaW) exerts anti-diabetic and immunomodulatory activities in diabetic animal models. Here, we used primary cultures of renal proximal tubule epithelial cells derived from type-2-diabetic (D-RPTEC)
R Meier et al.
European journal of biochemistry, 236(3), 796-805 (1996-03-15)
The identities of the upstream activators of the mitogen-activated protein (MAP) kinase homologues termed stress-activated-protein (SAP) kinase-1 (also known as JNK or SAPK) and SAP kinase-2 (also known as p38, RK and CSBP) were investigated in rat PC12 cells and
Tianxiao Gao et al.
Proceedings of the National Academy of Sciences of the United States of America, 119(4) (2022-01-26)
Proinflammatory cytokine production by innate immune cells plays a crucial role in inflammatory diseases, but the molecular mechanisms controlling the inflammatory responses are poorly understood. Here, we show that TANK-binding kinase 1 (TBK1) serves as a vital regulator of proinflammatory
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