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Merck
CN

137151

SAFC

2-巯基乙醇

EMPROVE® EVOLVE

制药生产

别名:

β-巯基乙醇, 2-羟乙基硫醇, BME, 硫代二甘醇

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About This Item

线性分子式:
HSCH2CH2OH
CAS号:
分子量:
78.13
Beilstein:
773648
MDL编号:
UNSPSC代码:
12161504

蒸汽密度

2.69 (vs air)

质量水平

蒸汽压

1 mmHg ( 20 °C)

形式

liquid

expl. lim.

18 %

浓度

14.3 M (pure liquid)
99.0-101.0 % (w/w)

杂质

≤1.0% related substances (GC) 2,2-Dithiodiethanol

折射率

n20/D 1.500 (lit.)

bp

157 °C (lit.)

密度

1.114 g/mL at 25 °C (lit.)

适用性

corresponds for identity (IR)

应用

pharma/biopharma processes

储存温度

2-8°C

SMILES字符串

OCCS

InChI

1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2

InChI key

DGVVWUTYPXICAM-UHFFFAOYSA-N

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一般描述

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

应用

BME 适用于在聚丙烯酰胺凝胶电泳前还原蛋白质二硫键,通常用于 SDS-PAGE 的样品缓冲液,浓度为 5%。 切割分子间(亚基之间)二硫键允许蛋白质的亚基在 SDS-PAGE 上独立分离。 切割分子内(亚基内)二硫键可使亚基完全变性,从而使每个肽根据其链长迁移,而不受二级结构的影响。

分析说明

purity (GC) ≥99.0%

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语:

Danger

危险分类

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

储存分类代码

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°C)

74 °C - closed cup

法规信息

危险化学品

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