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COA分析证书/COQ

12-140

Src Substrate Peptide

Name: Src Substrate Peptide
Brand: MM

Src Substrate Peptide primarily used in Kinase Assays.

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About This Item

UNSPSC代码:

12352202

eCl@ss:

32160405

NACRES:

NA.41

质量水平

100

分子量

M_w 1670 Da (1.67 kDa)

制造商/商品名称

Upstate^®

技术

activity assay: suitable (kinase)

NCBI登记号

NM_005417.3
NM_198291.1

UniProt登记号

P12931

运输

wet ice

基因信息

human ... SRC(6714)

一般描述

Synthetic peptide (KVEKIGEGTYGVVYK) corresponding to amino acids 6-20 of p34^cdc2.

生化/生理作用

Protein Target: Src

Target Sub-Family: TK

质量

Routinely evaluated in a protein kinase assay as a substrate for Src (p60^c-src), (14-117) or Lck (p56^lck), active (14-379).

外形

Lyophilized powder

储存及稳定性

Stable for 2 years at -20°C

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cells.

B Y Chang et al.

Molecular and cellular biology, 18(6), 3245-3256 (1998-06-20)

To isolate and characterize proteins that interact with the unique domain and SH3 and SH2 domains of Src and potentially regulate Src activity, we used the yeast two-hybrid assay to screen a human lung fibroblast cDNA library. We identified RACK1

Contraction regulation of Akt in rat skeletal muscle.

Kei Sakamoto et al.

The Journal of biological chemistry, 277(14), 11910-11917 (2002-01-26)

The protein serine/threonine kinase Akt/protein kinase B has been recognized as a critical signaling mediator for multiple cell systems. The function of Akt in skeletal muscle is not well understood, and whether contractile activity stimulates Akt activity has been controversial.

Eicosanoid activation of extracellular signal-regulated kinase1/2 in human epidermoid carcinoma cells.

C K Szekeres et al.

The Journal of biological chemistry, 275(49), 38831-38841 (2000-08-23)

12(S)-Hydroxyeicosatetraenoic acid (12(S)-HETE), a 12-lipoxygenase metabolite of arachidonic acid, has multiple effects on tumor and endothelial cells, including stimulation of invasion and angiogenesis. However, the signaling mechanisms controlling these physiological processes are poorly understood. In a human epidermoid carcinoma cell

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