ligand
(Sulfoethyl)
质量水平
描述
strong cation exchanger, suspension in 20% ethanol and 150 mM NaCl (40-90 µm)
无菌性
sterile (Caustic Stable)
产品线
Fractogel®
形式
resin
特殊分析物
MAbs
参数
220 cm/hr flow rate
8 bar max. pressure
基质活性基团
methacrylate
平均粒径
40-90 μm
容量
160 mg binding capacity (lysozyme/ml of resin)
转变温度
flash point 35 °C (calculated)
应用
recombinant protein
vaccine development
分离技术
cation exchange
strong cation exchange
储存温度
2-30°C
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一般描述
Strong cation exchange Fractogel® resin featuring the tentacle technology, for purification of basic and neutral proteins (e.g. antibodies) and peptides
特点和优势
Fractogel® EMD SE Hicap (M) features include:
- Tentacle technology provides high yield, selectivity, and focused elution
- High loading capacity combined with high purity at lower elution volumes
- Compatibility with 2.5 % (v/v) aqueous benzyl alcohol containing 150 mM NaCl storage solution
包装
- 1.14894.0100: Fractogel® EMD SE Hicap (M) Resin 100ml
- 1.14894.0010: Fractogel® EMD SE Hicap (M) Resin 10ml
- 1.14894.0500: Fractogel® EMD SE Hicap (M) Resin 500ml
- 1.14894.5000: Fractogel® EMD SE Hicap (M) Resin 5L
Plastic bottle
分析说明
Appearance: Milky turbid suspension,free from impurities(foreign particles)
Microscopic evaluation: Uniform spherical particles,no agglomerates,no fines
Extractable matter (water): ≤ 0.08 %
Cerium: ≤ 20 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (lysozyme): 120 - 160 mg/ml
Functional test (b:a): ≤ 0.20
Functional test: Separation of chymotrypsinogen A and lysozyme
Microscopic evaluation: Uniform spherical particles,no agglomerates,no fines
Extractable matter (water): ≤ 0.08 %
Cerium: ≤ 20 µg/g
Pressure drop(column: ID=1.6 cm, L=10 cm at 5 ml/min): ≤ 1.0 bar
Particle size (d10): 37 - 45 µm
Particle size (d50): 48 - 60 µm
Particle size (d90): 63 - 77 µm
Colony forming units (TAMC + TYMC): ≤ 100 CFU/ml
Endotoxins: ≤ 1.00 EU/ml
Protein binding capacity (lysozyme): 120 - 160 mg/ml
Functional test (b:a): ≤ 0.20
Functional test: Separation of chymotrypsinogen A and lysozyme
法律信息
FRACTOGEL is a registered trademark of Merck KGaA, Darmstadt, Germany
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警示用语：
Warning
危险声明
危险分类
Flam. Liq. 3
WGK
WGK 3
闪点(°F)
95.0 °F
闪点(°C)
35 °C
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