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Merck
CN
所有图片(2)

文件

1.07478

SAFC

1,2-丙二醇

EMPROVE® EXPERT, Ph. Eur., BP, USP

Pharma Manufacturing

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别名:
1,2-Propanediol, 1,2-Propylene glycol
线性分子式:
CH3CH(OH)CH2OH
CAS号:
57-55-6
分子量:
76.09
MDL编号:
MFCD00064272
UNSPSC代码:
12352104
EC索引号:
200-338-0

Agency

BP
Ph. Eur.
USP

质量水平

500

蒸汽压

0.11 hPa ( 20 °C)

产品线

EMPROVE® EXPERT

检测方案

≥99.5% (GC)

形式

liquid

自燃温度

371 °C

expl. lim.

2.4-17.4 % (v/v)

折射率

n20/D 1.43

pH值（酸碱度）

6-8 (20 °C, 100 g/L in H2O)

bp

188 °C/1013 hPa

mp

-59 °C

转变温度

flash point 99 °C

密度

1.04 g/cm3 at 20 °C

应用

liquid formulation
ophthalmics
parenterals
parenterals
pharmaceutical
semi-solid formulation

储存温度

2-30°C

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

相关类别

一般描述

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Propylene glycol is used as solvent in a variety of liquid formulations.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

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Strategies for the Development of Safe and Effective Pediatric Formulations

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

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Pediatric Formulations

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

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