Cellvento^® ModiFeed Gal- COMP

Cellvento^® ModiFeed Gal- COMP is part of the ModiFeed platform. It is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode, while simultanously reducing galactosylation on the protein of interest. It is recommened in combination with the production media Cellvento^® 4CHO and EX-CELL^® Advanced CHO Fed-batch medium or other production media.

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Glycosylation is known to have effects on the biological activity, solubility, serum half-life, and saftey of therapeutic proteins. Control of protein glycosylation processes, such as galactosylation, while maximizing productivity is key for successful mAb process development and production. Cellvento^® ModiFeed Gal- COMP was developed to increase G0(F), while maintaining or improving titer in CHO fed-batch processes.

Formulated to contain 143.6 grams of powder per liter of feed.

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany