推荐产品
生物来源
rabbit
质量水平
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
human
包装
antibody small pack of 25 μg
制造商/商品名称
Upstate®
技术
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
ambient
靶向翻译后修饰
unmodified
基因信息
human ... AGO2(27161)
一般描述
该基因可编码一个在RNA干扰中起作用的Argonaute蛋白家族成员。所编码的蛋白质是高度碱性的,并且包含PAZ和PIWI结构域。它可能与dicer1发生相互作用,并在短干扰RNA介导的基因沉默中发挥作用。
其为RNA诱导的沉默复合物(RISC)提供核酸内切酶活性。可切割与RISC结合的siRNA/mRNA异源双链体。其对于胚胎发育以及RNA介导的基因沉默(RNAi)至关重要。
其为RNA诱导的沉默复合物(RISC)提供核酸内切酶活性。可切割与RISC结合的siRNA/mRNA异源双链体。其对于胚胎发育以及RNA介导的基因沉默(RNAi)至关重要。
特异性
可识别Ago 2,也被称为真核翻译起始因子2C、2(EIF2C 2)、MGC3183和Q10。
免疫原
GST融合蛋白,对应人argonaute 2(Ago2)的7-48位残基。
应用
抗Ago 2抗体是一种兔多克隆抗体,可用于检测Ago 2(也称为argonaute 2) & 其已在WB应用中进行测试。
质量
其已在RIPA和HeLa细胞胞质裂解液中通过免疫印迹进行了常规评估。
目标描述
100kda
外形
形式:纯化
分析说明
对照
HeLa细胞裂解液,HL-60细胞裂解液
HeLa细胞裂解液,HL-60细胞裂解液
其他说明
浓度:请参考批次特异性浓缩物的分析证书。
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品?
试试我们的产品选型工具.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
法规信息
新产品
Two-step cleavage of hairpin RNA with 5' overhangs by human DICER.
BMC Molecular Biology null
Cytogenetic and genome research, 162(1-2), 10-27 (2022-03-31)
Long noncoding RNA FOXD2 adjacent opposite strand RNA1 (FOXD2-AS1) plays an oncogenic role in various cancers, including gastric cancer (GC). However, the function of FOXD2-AS1 in regulating radiosensitivity of GC cells and its underlying molecular mechanisms have not been elucidated.
Genome research, 20(10), 1398-1410 (2010-08-20)
Animal microRNA sequences are subject to 3' nucleotide addition. Through detailed analysis of deep-sequenced short RNA data sets, we show adenylation and uridylation of miRNA is globally present and conserved across Drosophila and vertebrates. To better understand 3' adenylation function
Genomics, 82(3), 323-330 (2003-08-09)
A number of genes have been identified as members of the Argonaute family in various nonhuman organisms and these genes are considered to play important roles in the development and maintenance of germ-line stem cells. In this study, we identified
Molecular cancer, 23(1), 113-113 (2024-05-28)
The role of circRNAs in hepatocellular carcinoma (HCC) progression remains unclear. CircPIAS1 (circBase ID: hsa_circ_0007088) was identified as overexpressed in HCC cases through bioinformatics analysis. This study aimed to investigate the oncogenic properties and mechanisms of circPIAS1 in HCC development.
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门