推荐产品
生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
mouse, human, rat
制造商/商品名称
Upstate®
技术
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... PTPRA(5786)
mouse ... Ptpra(19262)
rat ... Ptpra(25167)
特异性
PTP alpha isoform
免疫原
N-terminal GST-tagged fusion protein corresponding to residues 505-793 of human PTP alpha (complete D2 catalytic domain).
应用
Anti-PTPα Antibody detects level of PTPα & has been published & validated for use in WB.
Research Category
Signaling
Signaling
Research Sub Category
Kinases & Phosphatases
Kinases & Phosphatases
质量
Routinely evaluated by immunoblot in in NIH 3T3 cell lysates.
目标描述
130kDa
外形
ImmunoAffinity Purified
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
储存及稳定性
1 year at -20°C
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
A Petrone et al.
Journal of cell science, 113 ( Pt 13), 2345-2354 (2000-06-15)
Transmembrane (receptor) tyrosine phosphatases are intimately involved in responses to cell-cell and cell-matrix contact. Several important issues regarding the targets and regulation of this protein family are now emerging. For example, these phosphatases exhibit complex interactions with signaling pathways involving
Two mechanisms activate PTPalpha during mitosis.
Zheng, X M and Shalloway, D
The Embo Journal, 20, 6037-6049 (2001)
An RPTP?/Src family kinase/Rap1 signaling module recruits myosin IIB to support contractile tension at apical E-cadherin junctions.
Gomez, GA; McLachlan, RW; Wu, SK; Caldwell, BJ; Moussa, E; Verma, S; Bastiani, M; Priya et al.
Molecular Biology of the Cell null
Eliot T McKinley et al.
PloS one, 8(11), e80207-e80207 (2013-11-22)
Sensitive and specific biomarkers of protein kinase inhibition can be leveraged to accelerate drug development studies in oncology by associating early molecular responses with target inhibition. In this study, we utilized unbiased shotgun phosphotyrosine (pY) proteomics to discover novel biomarkers
Chan Zhou et al.
Genome medicine, 8(1), 31-31 (2016-03-24)
Hepatic fibrosis is the underlying cause of cirrhosis and liver failure in nearly every form of chronic liver disease, and hepatic stellate cells (HSCs) are the primary cell type responsible for fibrosis. Long noncoding RNAs (lncRNAs) are increasingly recognized as
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