推荐产品
生物来源
rabbit
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
rat, human
种属反应性(根据同源性预测)
mammals
制造商/商品名称
Upstate®
技术
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... GRIN3A(116443)
特异性
NR3A
免疫原
对应于大鼠NR3A氨基酸1098-1113的多肽(SRKTELEEYQKTNRTC)
应用
抗NR3A抗体是针对NR3A的抗体,可用于WB。
研究子类别
氧化应激
神经退行性疾病
氧化应激
神经退行性疾病
研究类别
神经科学
神经科学
质量
已通过免疫印迹对大鼠脑微粒体蛋白的制剂进行常规评估
目标描述
130kDa
外形
0.1M Tris-甘氨酸,pH 7.4,0.15M NaCl,0.05%叠氮化钠,然后添加甘油至30%
形式:纯化
蛋白A层析
储存及稳定性
在-20°C下可保存2年
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
Hoau-Yan Wang et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 29(35), 10961-10973 (2009-09-04)
Alzheimer's disease (AD) is characterized by synaptic dysfunction and cardinal neuropathological features including amyloid plaques and neurofibrillary tangles. Soluble amyloid-beta (Abeta) can suppress synaptic activities by interacting with alpha7 nicotinic acetylcholine receptors (alpha7nAChRs). Here, we show that alpha7nAChR and NMDA
Developmental regulation of the NMDA receptor subunits, NR3A and NR1, in human prefrontal cortex.
Henson, MA; Roberts, AC; Salimi, K; Vadlamudi, S; Hamer, RM; Gilmore, JH; Jarskog, LF; Philpot, BD
Cerebral Cortex (1991)
Roles of diverse glutamate receptors in brain functions elucidated by subunit-specific and region-specific gene targeting.
Mori, Hisashi and Mishina, Masayoshi
Life Sciences, 74, 329-336 (2003)
Amino terminal domain regulation of NMDA receptor function.
Herin, Greta Ann and Aizenman, Elias
European Journal of Pharmacology, 500, 101-111 (2004)
Plinio D Favaro et al.
PLoS biology, 16(12), e2006838-e2006838 (2018-12-27)
The disc-large (DLG)-membrane-associated guanylate kinase (MAGUK) family of proteins forms a central signaling hub of the glutamate receptor complex. Among this family, some proteins regulate developmental maturation of glutamatergic synapses, a process vulnerable to aberrations, which may lead to neurodevelopmental
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