生物来源
rabbit
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
rat, rabbit
制造商/商品名称
Upstate®
技术
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型
IgG
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... GRIK5(2901)
特异性
KA2
免疫原
21 residue synthetic peptide (KTSPPRPRPGPTGPRELTEHE) corresponding to the c-terminus of rat KA2 with a lysine added to the n-terminus
应用
Anti-KA2/GRIK5 (Kainate Receptor) Antibody is an antibody against KA2/GRIK5 (Kainate Receptor) for use in IC, IH, IP & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins
Neurodegenerative Diseases
Neurochemistry & Neurotrophins
Neurodegenerative Diseases
质量
routinely evaluated by immunoblot on rat brain microsomal preparation
目标描述
123kDa
外形
Protein G Chromatography
Format: Purified
of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
储存及稳定性
2 years at -20°C
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
S Mehta et al.
The Journal of biological chemistry, 276(19), 16092-16099 (2001-03-30)
Recent studies have demonstrated that kainate receptors are associated with members of the SAP90/PSD-95 family (synapse-associated proteins (SAPs)) in neurons and that SAP90 can cluster and modify the electrophysiological properties of GluR6/KA2 kainate receptors when co-expressed in transfected cells. In
Functional cooperation between KA2 and GluR6 subunits is involved in the ischemic brain injury.
Hai-Xia Jiang, Qiu-Hua Guan, Dong-Sheng Pei, Guang-Yi Zhang
Journal of Neuroscience Research null
Synaptic expression of the high-affinity kainate receptor subunit KA2 in hippocampal cultures
Roche, K. W. and Huganir, R. L.
Neuroscience, 69, 383-393 (1995)
A Herb et al.
Neuron, 8(4), 775-785 (1992-04-01)
A new ionotropic glutamate receptor subunit termed KA-2, cloned from rat brain cDNA, exhibits high affinity for [3H]kainate (KD approximately 15 nM). KA-2 mRNA is widely expressed in embryonic and adult brain. Homomeric KA-2 expression does not generate agonist-sensitive channels
J H Brandstätter et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 17(23), 9298-9307 (1997-12-31)
The synaptic localization of the kainate receptor subunits GluR6/7 and KA2 and of the ionotropic glutamate receptor subunits delta1/2 was studied in the rat retina using receptor-specific antisera. GluR6/7 and KA2 were present in both synaptic layers of the retina:
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