05-533
磷酸化CaM激酶II抗体，α亚基，Thr286，克隆22B1
clone 22B1, Upstate®, from mouse
别名:
Anti-Anti-CAMKA, Anti-Anti-CaMKIINalpha, Anti-Anti-CaMKIIalpha, Anti-Anti-MRD53, Anti-Anti-MRT63
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
22B1, monoclonal
Species reactivity:
rat
Application:
western blot
Technique(s):
western blot: suitable
Citations:
15
Uniprot accession no.:
产品名称
磷酸化CaM激酶II抗体，α亚基，Thr286，克隆22B1, clone 22B1, Upstate®, from mouse
biological source
mouse
antibody form
purified antibody
antibody product type
primary antibodies
clone
22B1, monoclonal
species reactivity
rat
manufacturer/tradename
Upstate®
technique(s)
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pThr286)
Quality Level
Gene Information
human ... CAMK2A(815)
Analysis Note
已通过免疫印迹对大鼠脑微粒体蛋白的制剂进行常规评估
Application
可使用这种磷酸化CaM激酶II抗体（α亚基，Thr286，克隆22B1）检测磷酸化CaM激酶II，该抗体经验证可用于WB。
Biochem/physiol Actions
磷酸化CaM激酶II α亚基
General description
50kDa
Immunogen
对应于大鼠CaM激酶IIα亚基残基281-294的肽；可识别苏氨酸286处磷酸化的CaM激酶II
Physical form
形式：纯化
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
Su-Ying Cui et al.
Journal of neurochemistry, 136(3), 609-619 (2015-11-13)
The Ca(2+) modulation in the dorsal raphe nucleus (DRN) plays an important role in sleep-wake regulation. Calmodulin-dependent kinase II (CaMKII) is an important signal-transducing molecule that is activated by Ca(2+) . This study investigated the effects of intracellular Ca(2+) /CaMKII
Overexpression of calbindin-D28K in hippocampal progenitor cells increases neuronal differentiation and neurite outgrowth.
Kim, JH; Lee, JA; Song, YM; Park, CH; Hwang, SJ; Kim, YS; Kaang, BK; Son, H
Faseb Journal null
B L Patton et al.
Molecular biology of the cell, 4(2), 159-172 (1993-02-01)
We have visualized the distribution of autophosphorylated type II CaM kinase in neural tissue with the use of two complementary antibodies: a monoclonal antibody that binds to the alpha and beta subunits of the kinase only when they are autophosphorylated
Integrins modulate fast excitatory transmission at hippocampal synapses.
Kramar, EA; Bernard, JA; Gall, CM; Lynch, G
The Journal of Biological Chemistry null
Taghi Manshouri et al.
Cancer research, 71(11), 3831-3840 (2011-04-23)
Signals emanating from the bone marrow microenvironment, such as stromal cells, are thought to support the survival and proliferation of the malignant cells in patients with myeloproliferative neoplasms (MPN). To examine this hypothesis, we established a coculture platform [cells cocultured
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