05-435
Anti-Lck Antibody, clone 3A5
clone 3A5, Upstate®, from mouse
别名:
Anti-IMD22, Anti-LSK, Anti-YT16, Anti-p56lck, Anti-pp58lck
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
3A5, monoclonal
Application:
immunoprecipitation (IP)
western blot
western blot
Species reactivity:
mouse, human, rat
Citations:
11
Technique(s):
immunoprecipitation (IP): suitable
western blot: suitable
western blot: suitable
Uniprot accession no.:
产品名称
Anti-Lck Antibody, clone 3A5, clone 3A5, Upstate®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
3A5, monoclonal
species reactivity
mouse, human, rat
manufacturer/tradename
Upstate®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG2bκ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... LCK(3932)
Analysis Note
Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
routinely evaluated by immunoblot on RIPA lysates from Jurkat cells
Application
Research Category
Signaling
Signaling
Research Sub Category
Immunological Signaling
Immunological Signaling
This Anti-Lck Antibody, clone 3A5 is validated for use in IP, WB for the detection of Lck.
Biochem/physiol Actions
Recognizes Lck.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
56 kDa
Immunogen
GST-fusion to residues 1-225 of murine Lck
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 04-372
Physical form
Format: Purified
Protein A purified
Protein A purified antibody in 100uL of 10mM PBS, pH 7.4
Preparation Note
Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
The differential expression of LCK and BAFF-receptor and their role in apoptosis in human lymphomas.
Jennifer C Paterson, Sara Tedoldi, Andrew Craxton, Margaret Jones, Martin-Leo Hansmann et al.
Haematologica null
Jing Jin et al.
Molecular and cellular biology, 36(6), 1007-1018 (2016-01-13)
The heat shock protein 90 (HSP90) and cell division cycle 37 (CDC37) chaperones are key regulators of protein kinase folding and maturation. Recent evidence suggests that thermodynamic properties of kinases, rather than primary sequences, are recognized by the chaperones. In
Tiphaine Douanne et al.
Open biology, 14(2), 230456-230456 (2024-02-28)
Cytotoxic T lymphocytes (CTLs) are key effectors of the adaptive immune system that recognize and eliminate virally infected and cancerous cells. In naive CD8+ T cells, T-cell receptor (TCR) engagement drives a number of transcriptional, translational and proliferation changes over
B Omri et al.
Journal of neurochemistry, 67(4), 1360-1364 (1996-10-01)
The lck gene product, p56lck, is a member of the src-related family of protein tyrosine kinases. It is known as lymphocyte specific and involved in thymocyte development and in the immune response mediated by the T cell receptor. We report
Association of SRC-related kinase Lyn with the interleukin-2 receptor and its role in maintaining constitutive phosphorylation of JAK/STAT in human T-cell leukemia virus type 1-transformed T cells.
Shuh, M; Morse, BA; Heidecker, G; Derse, D
Journal of virology null
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