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Merck
CN
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主要文件

04-539

Sigma-Aldrich

Anti-MAPKAP-K2 Antibody, clone 7H4.2

clone 7H4.2, Upstate®, from mouse

别名:

MAPK-activated protein kinase 2, MAPKAP kinase 2

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

7H4.2, monoclonal

种属反应性

human, rat, mouse

制造商/商品名称

Upstate®

技术

immunoprecipitation (IP): suitable
western blot: suitable

同位素/亚型

IgG

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... MAPKAPK2(9261)

免疫原

KLH-conjugated synthetic peptide of the C-terminus of the long form of human MAPKAP-K2.

应用

Suggested dilutions:
Immunoblot Analysis: 1:500
Immunoprecipitation: 1:20
Anti-MAPKAP-K2 Antibody, clone 7H4.2 detects level of MAPKAP-K2 & has been published & validated for use in IP & WB.
Research Category
Signaling
Research Sub Category
MAP Kinases

Kinases & Phosphatases

质量

Routinely evaluated by immunoblot.

目标描述

45 kDa

外形

Protein A purified
200 µg (1 mg/mL) of mouse monoclonal IgG in PBS containing 0.1% sodium azide.
Format: Purified

储存及稳定性

2 years at -20°C from date of shipment.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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L Xu et al.
Oncogene, 25(21), 2987-2998 (2006-01-13)
Although cell invasion is a necessary early step in cancer metastasis, its regulation is not well understood. We have previously shown, in human prostate cancer, that transforming growth factor beta (TGFbeta)-mediated increases in cell invasion are dependent upon activation of
Isaac A Manke et al.
Molecular cell, 17(1), 37-48 (2005-01-05)
The cellular response to DNA damage is mediated by evolutionarily conserved Ser/Thr kinases, phosphorylation of Cdc25 protein phosphatases, binding to 14-3-3 proteins, and exit from the cell cycle. To investigate DNA damage responses mediated by the p38/stress-activated protein kinase (SAPK)
Matthieu Lemaire et al.
Cell cycle (Georgetown, Tex.), 5(15), 1649-1653 (2006-07-25)
CDC25B is one of the three human phosphatases that are involved in the control of the activation of cyclin-dependent kinases. CDC25B participates in regulating entry into mitosis and appears to play a key role in the checkpoint response to DNA
Ainsley A Culbert et al.
The Journal of biological chemistry, 281(33), 23658-23667 (2006-06-16)
MAPK-activated protein kinase 2 (MAPKAP K2 or MK2) is one of several kinases directly regulated by p38 MAPK. A role for p38 MAPK in the pathology of Alzheimer disease (AD) has previously been suggested. Here, we provide evidence to suggest

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