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Merck
CN

04-1584

Anti-Interleukin-2 (IL-2) Antibody, clone 3F9

clone AB12.38.35C3.3F9, from mouse

别名:

interleukin 2, involved in regulation of T-cell clonal expansion, aldesleukin, T cell growth factor, lymphokine, Aldesleukin, interleukin-2, T-cell growth factor

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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产品名称

Anti-Interleukin-2 (IL-2) Antibody, clone 3F9, clone AB12.38.35C3.3F9, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

AB12.38.35C3.3F9, monoclonal

species reactivity

human

technique(s)

western blot: suitable

isotype

IgG2bκ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... IL2(3558)

Analysis Note

Control
Human IL-2 recombinant protein
Evaluated by Western Blot in lysate from cells expressing human IL-2 recombinant protein.

Western Blot Analysis: 0.5 µg/mL of this antibody detected 10 µg of human IL-2 recombinant protein.

Application

Detect Interleukin-2 (IL-2) using this Anti-Interleukin-2 (IL-2) Antibody, clone 3F9 validated for use in WB.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Interleukin-2 (IL-2) is commonly considered a pro-inflammatory cytokine that stimulated T-cell-dependent immune reactions and control regulatory T cells or Tregs. Structurally, IL-2 is thought to have a 4-helix-bundle-type fold and uses a novel type I cytokine receptor (IL-21R) with the common gamma chain cytokine receptor. IL-2 also may intensify Th1-mediated diseases, including autoimmune arthritis and may also be interesting clinical targets for those diseases. IL-2 has also been implicated as a possible therapy for infection and cancer. Anti-tumor therapies that include a combination of recombinant IL-2 and recombinant interferon alpha have been promising in clinical studies.
~15 kDa observed

Immunogen

Full length recombinant protein corresponding to human IL-2.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Guohui Li et al.
Molecular medicine reports, 17(2), 3350-3355 (2017-12-20)
Uremia is a serious threat to health. Infection associated with inflammation frequently occurs in patients with uremia during hemodialysis. This study aimed to investigate the association between serum inflammatory factors and uremia in patients prior to and following hemodialysis. Patients

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