推荐产品
生物来源
mouse
质量水平
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
PSG3, monoclonal
种属反应性
human
制造商/商品名称
Upstate®
技术
immunofluorescence: suitable
western blot: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... ARID1A (8289)
特异性
BAF250a/ARID1a
免疫原
GST融合蛋白，对应人BAF250a/ARID1a中部419个残基。
应用
抗BAF250a/ARID1A抗体，克隆PSG3是针对BAF250a/ARID1A的抗体，用于WB，ChIP，IC & IHC。
研究子类别
染色质生物学
转录因子
染色质生物学
转录因子
研究类别
表观遗传学&核功能
表观遗传学&核功能
质量
已通过免疫印迹进行常规评估。
目标描述
~270 kDa
外形
100 μg蛋白A纯化的小鼠单克隆IgG，溶于100 μL 1X PBS（pH 7.0，0.1%叠氮化物）中。
形式：纯化
蛋白A纯化
储存及稳定性
自运送之日起在-20°C下保存2年
法律信息
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Essential role of ARID2 protein-containing SWI/SNF complex in tissue-specific gene expression.
Xu, F; Flowers, S; Moran, E
The Journal of Biological Chemistry null
Zuqin Nie et al.
Molecular and cellular biology, 23(8), 2942-2952 (2003-04-01)
The SWI/SNF family of chromatin-remodeling complexes has been discovered in many species and has been shown to regulate gene expression by assisting transcriptional machinery to gain access to their sites in chromatin. Several complexes of this family have been reported
Xiaomei Wang et al.
The Biochemical journal, 383(Pt 2), 319-325 (2004-06-02)
p270 (ARID1A) is a member of the ARID family of DNA-binding proteins and a subunit of human SWI/SNF-related complexes, which use the energy generated by an integral ATPase subunit to remodel chromatin. ARID1B is an independent gene product with an
Coexistent ARID1A-PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling.
Chandler, RL; Damrauer, JS; Raab, JR; Schisler, JC; Wilkerson, MD; Didion, JP; Starmer et al.
Nature Communications null
Guillermo Pablo Vicent et al.
The Journal of biological chemistry, 285(4), 2622-2631 (2009-11-27)
Steroid hormones induce transcription of their responsive genes by complex mechanisms including synergism between the hormone receptors and other transcription factors. On the mouse mammary tumor virus (MMTV) promoter progesterone induction is mediated by the reciprocal synergism between progesterone receptor
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