跳转至内容
Merck
CN

03-0146-00

SMC® 淀粉样β42高灵敏度试剂盒

Used for ultrasensitive quantification of Amyloid Beta 1-42 (Aβ42) in human, rat or mouse plasma or cerebrospinal fluid (CSF)

别名:

Abeta 1-42 immunoassay kit, Abeta 42 Single Molecule Counting Kit, Abeta 42 immunoassay kit, Abeta 42 ultra-sensitive Immunoassay

登录 查看公司和协议定价

选择尺寸


关于此项目

UNSPSC代码:
12161503
NACRES:
NA.84
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

质量水平

产品线

SMC®

用途

 kit sufficient for 96 wells

种属反应性

human

制造商/商品名称

SMC®

技术

single molecule counting: suitable

输入

serum
plasma
cerebrospinal fluid (CSF)

相容性

for use with for use with FemtoQuest and SMCxPRO® instruments (validated)

运输

wet ice

储存温度

2-8°C

一般描述

SMC® 淀粉样蛋白 β 1-42 高灵敏度免疫检测试剂盒包含进行测定所需的所有试剂。该测定采用标准免疫测定工作流程,配置标准板形式。

测定方案与现有的夹心 ELISA 方法相似,但有两个主要区别:
1)洗脱缓冲液破坏三明治,分离标记的检测抗体用于进行定量。
2)Erenna 和 SMCxPRO® 免疫测定系统使用单分子计数(SMC®)技术检测分析物。

应用

Neuroscience/Neurological Disorders/Signaling

生化/生理作用

该捕获抗体识别淀粉样蛋白 β1-42 的 C 末端,具有对 Aβ42 的特异性。没有观察到与 Aβ38 和 Aβ40 的明显的交叉反应。

特点和优势

  • High Sensitivity Detection: Precisely quantifies Amyloid Beta 1-42 at femtogram/mL levels in plasma or CSF.
  • Improved Dynamic Range: Enhanced signal-to-noise ratio with reduced background interference for reliable assay performance.
  • User-Friendly Workflow: Utilizes a familiar sandwich immunoassay format while ensuring high sensitivity for Aβ1-42 detection.
  • Automation-Ready: Compatible with automated liquid handling systems, reducing manual steps and increasing lab efficiency.

包装

96 well assay

分析说明

  • Sensitivity: LLOQ 980 fg/mL* (SMCxPRO® Instrument
  • Standard Curve Range: 244-250,000 fg/mL
  • Intra-assay CV: <15%
  • Inter-assay CV: <20%
  • Linearity: CSF: 100%
  • Recovery: Plasma: 94% CSF: 92%

*Indicative LLOQ created from average of 14 independent in house runs, where >80% met same value defined with CV & Recovery +/- 20%. Refer to CoA for lot specific performance.
Neuroscience

Neurological Disorders

Neurodegenerative Diseases

Alzheimer′s Disease

法律信息

FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation

靶器官

Respiratory Tract

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

法规信息

含少量动物源组分生物产品
常规特殊物品
此项目有

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Chia-Liang Tsai et al.
Journal of clinical medicine, 8(10) (2019-10-09)
Nondemented people with a family history of Alzheimer's disease (ADFH) and the ApoE-4 allele have been demonstrated to show a trend for a higher probability of cognitive decline and aberrant levels of cognitive-related biomarkers. However, the potential interactive effects on

相关内容

通过适合的免疫检测产品,探索神经免疫和神经炎症细胞因子及神经退行性疾病生物标志物。

在强大的SMCxPRO®检测平台上,采用单分子计数(SMC®)高灵敏度免疫检测试剂盒,准确可靠地检测健康和病患来源的主要神经学蛋白分析物,进行神经科学研究。分析各种神经科学生物标志物,如神经丝蛋白轻链(NF-L)、胶质纤维酸性蛋白(GFAP)、Tau蛋白、β-淀粉样蛋白等。

Discover how to expand neuroscience biomarker research with high sensitivity immunoassays, such as Single Molecule Counting (SMC®) assays. These assays give researchers the tools they need to detect low-abundant blood-based biomarkers and expand biomarker options in neuroscience research.

Explore ultrasensitive immunoassay technology with SMC® technology, including its biomarker detection platform, advantages of high sensitivity assays, and more.

查看所有结果

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持