推荐产品
等级
certified reference material
质量水平
表单
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in acetonitrile
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
pharmaceutical (small molecule)
包装形式
single component solution
储存温度
−20°C
SMILES字符串
O=C1N(C)CC(N2[C@H](C3=CC(OCO4)=C4C=C3)C5=C(C(C=CC=C6)=C6N5)C[C@@]21[H])=O
InChI
1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
InChI key
WOXKDUGGOYFFRN-IIBYNOLFSA-N
基因信息
human ... PDE5A(8654)
一般描述
Tadalafil is an erectile-dysfunction drug marketed under the trade name Cialis®. This Certified Spiking Solution® is suitable for use in numerous testing applications such as clinical toxicology, forensic analysis, urine drug testing, or calibrator preparation.
应用
- Universal Quantitation of PDE5 Inhibitors: A study highlights the use of high-performance liquid chromatography with charged aerosol detection to universally quantitate undeclared phosphodiesterase-5 inhibitors, including tadalafil, in herbal dietary supplements. This method ensures the integrity of dietary supplements and protects consumers from potential health risks (Poplawska et al., 2013).
- Drug Screening with 3D-Printed Electrochemical Cells: Research developed a multi-sensor compatible 3D-printed electrochemical cell for voltammetric drug screening, applicable to tadalafil and other drugs. This innovative approach enhances drug analysis efficiency and accuracy, facilitating rapid screening in pharmaceutical research (Ferreira et al., 2021).
- Solid Dispersions for Enhanced Solubility: A study on the physical stability of solid dispersions of tadalafil in PVP-VA investigates the thermodynamic solubility of the drug, critical for improving bioavailability in pharmaceutical formulations. This research contributes to the development of more effective and reliable drug delivery systems (Wlodarski et al., 2015).
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Cialis is a registered trademark of Eli Lilly and Co.
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
35.6 °F - closed cup
闪点(°C)
2 °C - closed cup
法规信息
危险化学品
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