推荐产品
等级
certified reference material
质量水平
表单
liquid
特点
Snap-N-Spike®/Snap-N-Shoot®
包装
ampule of 1 mL
制造商/商品名称
Cerilliant®
浓度
1.0 mg/mL in methanol (as free base)
技术
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
应用
clinical testing
包装形式
single component solution
储存温度
−20°C
SMILES字符串
Cl.CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13
InChI
1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H
InChI key
FBSMERQALIEGJT-UHFFFAOYSA-N
基因信息
human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356)
一般描述
以商品名Thorazine或Largactil出售的氯丙嗪是一种用于治疗精神分裂症的典型抗精神病药。该认证的加标溶液®适合作为校准品或对照品中的起始材料用于从法医分析和临床毒理学到尿液药物检测的各种LC/MS或GC/MS应用。
法律信息
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
靶器官
Eyes
储存分类代码
3 - Flammable liquids
WGK
WGK 2
闪点(°F)
49.5 °F - closed cup
闪点(°C)
9.7 °C - closed cup
法规信息
危险化学品
Martin González-Andrade et al.
Journal of molecular recognition : JMR, 26(4), 165-174 (2013-03-05)
Protein-protein interactions play central roles in physiological and pathological processes. The bases of the mechanisms of drug action are relevant to the discovery of new therapeutic targets. This work focuses on understanding the interactions in protein-protein-ligands complexes, using proteins calmodulin
Adeline Gaillard et al.
Soins. Psychiatrie, (286)(286), 25-29 (2013-06-14)
The history of drug treatments, and particularly the discovery of certain molecules, led toan evolution in psychiatric practices. The discovery of the therapeutic properties of chlorpromazine in 1952 by Jean Delay and Pierre Deniker revolutionised the relational process between patients
Systemic uptake of chlorpromazine after delivery via retrobulbar injection.
Ruben Kuruvilla et al.
Archives of ophthalmology (Chicago, Ill. : 1960), 130(10), 1348-1349 (2012-10-10)
Antipsychotic therapy over half a century: a tale of discovery from chlorpromazine to aripiprazole.
Sridhar Natesan et al.
The National medical journal of India, 25(4), 193-195 (2013-01-03)
Stephanie L MacAllister et al.
Canadian journal of physiology and pharmacology, 91(1), 56-63 (2013-02-02)
Chlorpromazine (CPZ), a member of the largest class of first-generation antipsychotic agents, is known to cause hepatotoxicity in the form of cholestasis and hepatocellular necrosis in some patients. The mechanism of CPZ hepatotoxicity is unclear, but is thought to result
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