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Merck
CN

C-106

皮质醇标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

别名:

氢化可的松 溶液, 17-羟基皮质酮标准液, 皮质醇标准液

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化学文摘社编号:
50-23-7
NACRES:
NA.24
PubChem Substance ID:
329774841
UNSPSC Code:
41116107
EC Number:
200-659-6
MDL number:
MFCD00011654

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产品名称

皮质醇标准液 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

InChI key

JYGXADMDTFJGBT-VWUMJDOOSA-N

InChI

1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1

SMILES string

C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)C[C@H](O)[C@H]23

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing
clinical testing

format

single component solution

storage temp.

−20°C

Quality Level

300

Gene Information

human ... NR3C1(2908)

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相关类别

Application

该认证标准物质（CRM）还可作如下用途：
  • 开发基于直接竞争-酶联免疫分析法（DC-ELISA）的一次性免疫传感器，用于测定人唾液样品中的皮质醇
  • 使用液相色谱-串联质谱（LC-MS/MS）法定量分析人头发样品中的皮质醇
  • 通过自动固相萃取（SPE）结合液相色谱（LC）与电喷雾电离-串联质谱（ESI-MS3）对人发样品中的皮质醇和可的松进行选择性和敏感性分析
  • 通过 LC-MS/MS 法对人尿液中皮质醇、可的松及其三种四氢代谢物进行多残留测定
  • 通过离子液体分散液-液微萃取（IL-DLLME）结合液相色谱-紫外/可见（UV/Vis）检测估算人唾液中的皮质醇和可的松含量

Features and Benefits

  • 完全符合 ISO/IEC 17025 和 ISO 17034 认证
  • 附综合分析证书（CoA），包括稳定性、均匀性、浓度准确性、不确定性和可追溯性数据
  • 通过实时稳定性研究严格测试，以确保准确性和保质期
  • 使用合格的精密天平进行重量准备，以确保最小不确定性
  • 氩气环境下火焰密封，装入安瓿以便长期保存
  • 提供方便的 DEA 豁免格式，以提高实验室效率

General description

皮质醇或氢化可的松，也称为应激激素，是一种糖皮质激素类固醇。它由肾上腺释放，参与维持昼夜节律。通过LC-MS/MS在全血中对激素进行测定，以在新生儿中进行先天性肾上腺增生（CAH）的筛查，同时，通过LC-MS/MS在血清或血浆中对激素进行测定，以对多种疾病，包括库兴氏综合征、艾迪生氏病和席汉氏综合征进行确定。

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

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