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描述
1,2-dipalmitoyl-sn-glycero-3-phosphocholine
方案
>99% (TLC)
表单
powder
包装
pkg of 1 × 1 g (850355P-1g)
pkg of 1 × 200 mg (850355P-200mg)
pkg of 1 × 25 mg (850355P-25mg)
pkg of 1 × 500 mg (850355P-500mg)
制造商/商品名称
Avanti Research™ - A Croda Brand
脂质类型
phospholipids
cardiolipins
运输
dry ice
储存温度
−20°C
SMILES字符串
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O
InChI
1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3
InChI key
KILNVBDSWZSGLL-UHFFFAOYSA-N
一般描述
1,2-双十六酰基-sn-甘油-3-磷酰胆碱(DPPC)由不饱和磷脂酰胆碱(PC)通过直接的从头合成经由α1,2-二棕榈酰甘油二酯中间体而合成。磷酸胆碱转移酶酶催化1,2-二棕榈酰甘油二酯向DPPC转化。DPPC也能在重塑途径中通过不饱和PC的脱乙酰化而合成。
Avanti提供的磷脂酰胆碱产品列表旨在提供具有多种物理性质的化合物。可用产品包括短链（C3-C8是水溶性和吸湿性）、饱和、多不饱和和混合酸PC′s。所有产品均通过HPLC纯化，并采取特殊预防措施保护产品不发生氧化和水解。
应用
16:0 PC (DPPC)已用于制备、(TQ)脂质体、金纳米棒和氯化钙包埋脂质体以及用于生物物理研究的双分子层。
生化/生理作用
1,2-双十六酰基-sn-甘油-3-磷酰胆碱(DPPC)是一种表面活性剂，可降低表面张力。它可联用1,2-二油酰-sn-甘油-3磷酰胆碱(DOPC)制备脂质双分子层。DPPC可单独或联用其他磷脂进行有效的药物包埋和递送。
包装
20 mL透明玻璃螺旋盖样品瓶（850355P-1g）
20 mL透明玻璃螺旋盖样品瓶（850355P-500mg）
5 mL棕色玻璃螺旋盖样品瓶（850355P-200mg）
5 mL棕色玻璃螺旋盖样品瓶（850355P-25mg）
法律信息
Avanti Research is a trademark of Avanti Polar Lipids, LLC
通常也和此产品一起购买
产品编号
说明
价格
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Phenotypic basis for matrix stiffness-dependent chemoresistance of breast cancer cells to doxorubicin
Joyce MH, et al.
Frontiers in Oncology, 8, 203-208 (2018)
Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells
Chen X, et al.
Proceedings of the National Academy of Sciences of the USA, 103(31), 11724-11729 (2006)
Norbert Kučerka et al.
Langmuir : the ACS journal of surfaces and colloids, 33(12), 3134-3141 (2017-03-10)
Interactions of calcium (Ca2+) and zinc (Zn2+) cations with biomimetic membranes made of dipalmitoylphosphatidylcholine (DPPC) were studied by small angle neutron diffraction (SAND). Experiments show that the structure of these lipid bilayers is differentially affected by the two divalent cations.
M Mamusa et al.
Langmuir : the ACS journal of surfaces and colloids, 34(30), 8952-8961 (2018-07-07)
The emergence of antibiotic-resistant bacterial strains has fostered fundamental research to develop alternative antimicrobial strategies. Among the several systems proposed so far, the association complexes (nanoplexes) formed by transcription factor decoys (TFDs), i.e., short oligonucleotides targeting a crucial bacterial transcription
S Q Choi et al.
Nature communications, 2, 312-312 (2011-05-19)
Two-dimensional films of surface-active agents-from phospholipids and proteins to nanoparticles and colloids-stabilize fluid interfaces, which are essential to the science, technology and engineering of everyday life. The 2D nature of interfaces present unique challenges and opportunities: coupling between the 2D
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