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Merck
CN

M79204

Sigma-Aldrich

N -甲基吡咯烷

97%

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别名:
1-Methylpyrrolidine, N-Methylpyrrolidine, N-Methyltetrahydropyrrole
经验公式(希尔记法):
C5H11N
CAS号:
分子量:
85.15
Beilstein:
102445
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

97%

形式

liquid

bp

80-81 °C (lit.)

密度

0.819 g/mL at 25 °C (lit.)

SMILES字符串

CN1CCCC1

InChI

1S/C5H11N/c1-6-4-2-3-5-6/h2-5H2,1H3

InChI key

AVFZOVWCLRSYKC-UHFFFAOYSA-N

应用

N-甲基吡咯烷可用作制备以下成分的起始材料:
N-甲基吡咯烷-硼氢化锌(ZBHNMP)——这是一种用于还原醛,酮,酰氯和酯的还原剂。ZBHNMP还用于将醛和酮还原胺化为相应的胺。
N-烷基-N-甲基-吡咯烷鎓双(三氟甲磺酰基)亚胺离子液体。
N-甲基吡咯烷-2-酮氢三溴化物可用作烯烃的叠氮化催化剂。

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Chronic 2 - Flam. Liq. 2 - Skin Corr. 1A

WGK

WGK 3

个人防护装备

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

危险化学品

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Reductive amination of aldehydes and ketones to their corresponding amines with N-methylpyrrolidine zinc borohydride
Alinezhad H, et al.
Tetrahedron Letters, 50(6), 659-661 (2009)
N-methylpyrrolidine-2-one hydrotribromide: An efficient and new catalyst for the aziridination of alkenes using Chloramine-T under solvent free conditions
Jain SL, et al.
J. Mol. Catal. A: Chem., 256(1-2), 16-20 (2006)
A R Salomon et al.
Biochemistry, 35(42), 13568-13578 (1996-10-22)
The 42-residues beta-(1-42) peptide is the major protein component of amyloid plaque cores in Alzheimer's disease. In aqueous solution at physiological pH, the synthetic beta-(1-42) peptide readily aggregates and precipitates as oligomeric beta-sheet structures, a process that occurs during amyloid
Lijun Wei et al.
Carbohydrate research, 340(9), 1583-1590 (2005-06-01)
4'-Modified avermectin derivatives were designed and synthesized. Some of the new synthetic compounds showed excellent in vivo bioactivity against cabbage larvae when compared to commercially available avermectin B1a. In this synthesis, uncommon thioglycosyl sugar donors, prepared from the hydrolysis of
Pawel Mroz et al.
Nanomedicine : nanotechnology, biology, and medicine, 7(6), 965-974 (2011-06-08)
Functionalized fullerenes represent a new class of photosensitizer (PS) that is being investigated for photodynamic therapy (PDT) of various diseases, including cancer. We tested the hypothesis that fullerenes could be used to mediate PDT of intraperitoneal (IP) carcinomatosis in a

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