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Merck
CN

M1407

Sigma-Aldrich

丙二腈

≥99%

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别名:
二氰基甲烷
线性分子式:
CH2(CN)2
CAS号:
分子量:
66.06
Beilstein:
773697
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

质量水平

检测方案

≥99%

bp

220 °C (lit.)

mp

30-32 °C (lit.)

密度

1.049 g/mL at 25 °C (lit.)

储存温度

2-8°C

SMILES字符串

N#CCC#N

InChI

1S/C3H2N2/c4-2-1-3-5/h1H2

InChI key

CUONGYYJJVDODC-UHFFFAOYSA-N

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一般描述

丙二腈,一种弱氰基碳酸,是一种反应性超高的多功能化合物。这种结晶脂肪族腈可用作合成杂环化合物和聚合物的合成砌块。

应用

丙二腈可用于:
  • 碱促进的[1,6]-萘啶水上合成。†
  • γ--酮酰胺的合成。
  • 特殊杂环药物支架(包括吡啶、1,4-二氢吡啶、苯并吡喃[2,3-b]吡啶和二氢-1,4-二噻吩骨架)的制备。

包装

玻璃瓶封装

象形图

Skull and crossbonesEnvironment

警示用语:

Danger

危险分类

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Sens. 1

WGK

WGK 3

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

危险化学品

分析证书(COA)

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High-Performance Quinoline-Malononitrile Core as a Building Block for the Diversity-Oriented Synthesis of AIEgens
Z Guo, et al.
Angewandte Chemie (International Edition in English), 59, 9812-9825 (2020)
The chemistry of malononitrile.
F Freeman
Chemical reviews, 69(5), 591-624 (1969-10-01)
Kamila K Mentel et al.
Nature communications, 9(1), 2903-2903 (2018-07-27)
Electron transfer reactions are arguably the simplest chemical reactions but they have not yet ceased to intrigue chemists. Charge-separation and charge-recombination reactions are at the core of life-sustaining processes, molecular electronics and solar cells. Intramolecular electron donor-acceptor systems capture the
Bandita Datta et al.
Ultrasonics sonochemistry, 19(4), 725-728 (2012-02-14)
A one-pot three-component condensation of an aldehyde, malononitrile, and resorcinol has been achieved by ultrasound method. The reaction has been catalyzed by glycine in aqueous medium. This protocol afforded corresponding 2-amino-4H-chromenes in shorter reaction times, high yields and simple work-up
Tamer S Saleh et al.
Ultrasonics sonochemistry, 19(3), 491-497 (2011-11-29)
Novel fused pyrans were synthesized from the reaction of the tetrahydropyran-4-one with arylidine malononitriles. Different fused pyran derivatives were obtained from the mentioned reaction depending on type of catalyst used and type of energy used. Reactions were carried out under

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