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Merck
CN

CDS022173

伊马替尼

别名:

4-(4-甲基哌嗪-1-甲基)-N-[4-甲基-3-[[4-(吡啶-3-基)嘧啶-2-基]氨基]苯基]苯甲酰胺, 4-[(4-甲基-1-哌嗪)甲基]-N-[4-甲基-3-[[4-(3-吡啶)-2-嘧啶]氨基]苯基]苯甲酰胺, CGP 57148, N-(4-甲基-3-((4-(吡啶-3-基)嘧啶-2-基)氨基)苯基)-4-((4-甲基哌嗪-1-基)甲基)苯甲酰胺, 甲磺酸伊马替尼

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关于此项目

经验公式（希尔记法）:
C29H31N7O
化学文摘社编号:
152459-95-5
分子量:
493.60
UNSPSC Code:
12352200
PubChem Substance ID:
329795436
MDL number:
MFCD05662257
NACRES:
NA.21
Form:
solid

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InChI

1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)

SMILES string

O=C(C(C=C1)=CC=C1CN2CCN(C)CC2)NC3=CC(NC4=NC(C5=CN=CC=C5)=CC=N4)=C(C)C=C3

InChI key

KTUFNOKKBVMGRW-UHFFFAOYSA-N

description

AldrichCPR

form

solid

Gene Information

human ... ABL1(25), KIT(3815), PDGFRB(5159)

General description

伊马替尼(Imatinib)是一种苯甲酰胺衍生物，用作特定酪氨酸激酶受体抑制剂。可抑制费城(Philadelphia, Ph)染色体异常导致的断裂点簇集区(BCR)-Abelson(ABL)融合蛋白。伊马替尼也用作强效的凋亡诱导剂和抗肿瘤药。

Other Notes

请注意，Sigma-Aldrich将本品作为一系列特殊化学品的一部分提供给早期发现研究人员。Sigma-Aldrich不收集本品的分析数据。买方承担确认产品特性和/或纯度的责任。所有销售均为最终销售。

尽管SIGMA-ALDRICH的标准条款和条件以及SIGMA-ALDRICH和买方之间的协议中包含所有合同条款，但无论是在法律、交易过程、执行过程中的行为、以及贸易或其他方面的使用等过程中，SIGMA-ALDRICH按“原样”销售此产品并且并对此产品不作任何陈述或担保，包括：(A)适销性担保；(B)特定用途适用性担保；或(C)未侵犯第三方知识产权担保。

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Carc. 2 - Lact. - Muta. 2 - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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