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CDS021593

Sigma-Aldrich

吡格列酮

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50 MG
¥588.44

¥588.44


预计发货时间2025年5月16日详情


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50 MG
¥588.44

About This Item

经验公式(希尔记法):
C19H20N2O3S
分子量:
356.44
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:

¥588.44


预计发货时间2025年5月16日详情


获取大包装报价

描述

AldrichCPR

表单

solid

SMILES字符串

O=C(N1)C(SC1=O)CC(C=C2)=CC=C2OCCC(N=C3)=CC=C3CC

InChI

1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)

InChI key

HYAFETHFCAUJAY-UHFFFAOYSA-N

基因信息

human ... PPARG(5468)

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230950648469MSML1884
Ciglitazone A potent thiazolinedione (TDZ) type anti-hyperglycemic agent and a selective PPARγ agonist (EC₅₀ = 3 µM).

230950

Ciglitazone

form

solid

form

solid

form

solid

form

powder

description

AldrichCPR

description

-

description

-

description

-

Gene Information

human ... PPARG(5468)

Gene Information

-

Gene Information

-

Gene Information

-

其他说明

请注意,Sigma-Aldrich 向早期发现研究人员提供该产品,作为独特化学品集合的一部分。Sigma-Aldrich 不收集本品的分析数据。买方负责确认产品标识和/或纯度。所有销售均为最终产品。
即使Sigma-Aldrich的标准销售条款和条件或Sigma-Aldrich与买方之间的协议中有任何相反的规定,SIGMA-ALDRICH仍“按原样”销售本产品,且不就本产品做出任何声明或保证,包括 (A) 适销性保证,(B) 特定用途的适合性保证,或 (C) 针对第三方知识产权侵权的保证,无论是否由法律、交易过程、履行过程、贸易使用或其他原因引起。

象形图

Health hazardExclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral - Carc. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


  • 历史批次信息供参考:

    分析证书(COA)

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    Mukul R Jain et al.
    Liver international : official journal of the International Association for the Study of the Liver, 38(6), 1084-1094 (2017-11-23)
    Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are common clinico-pathological conditions that affect millions of patients worldwide. In this study, the efficacy of saroglitazar, a novel PPARα/γ agonist, was assessed in models of NAFLD/NASH. HepG2 cells treated with
    Lourdes Ibáñez et al.
    The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 61(4), 446-453 (2017-07-18)
    Polycystic ovary syndrome (PCOS) is an increasingly prevalent disorder in adolescent girls, commonly presenting with hirsutism/oligomenorrhea, commonly treated with an oral contraceptive (OC), and commonly followed by oligoanovulatory subfertility. We tested whether an intervention targeting the reduction of hepato-visceral adiposity
    Tsung-Yi Cheng et al.
    Journal of the Chinese Medical Association : JCMA, 80(11), 683-689 (2017-10-04)
    Hepatopulmonary syndrome (HPS) is characterized by oxygen desaturation and increased intrapulmonary shunting formation in cirrhosis. Due to an unclarified mechanism, there is still no effective therapy except liver transplantation. Recent studies revealed that pulmonary angiogenesis may participate in pathogenesis, in
    Li Sun et al.
    Life sciences, 232, 116609-116609 (2019-06-30)
    Pioglitazone has been demonstrated to exert anti-fibrotic and renoprotective effects. But the detailed pharmacological mechanisms have not been clearly revealed. The present study aimed to investigate the possible mechanisms of pioglitazone in these two effects. TGF-β1-stimulated HK-2 cells and unilateral
    Lawrence H Young et al.
    Circulation, 135(20), 1882-1893 (2017-03-02)
    Insulin resistance is highly prevalent among patients with atherosclerosis and is associated with an increased risk for myocardial infarction (MI) and stroke. The IRIS trial (Insulin Resistance Intervention after Stroke) demonstrated that pioglitazone decreased the composite risk for fatal or

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